QQ客服 官方微博 反馈留言

浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2016     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery and Structural Optimization of N5-Substituted 6,7-Dioxo-6,7-dihydropteridines as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 15, 页码: 7111-7124 作者:  Hao, Yongjia;  Wang, Xia;  Zhang, Tao;  Sun, Deheng;  Tong, Yi 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2673-2680 作者:  Xiao, Qiang;  Qu, Rong;  Gao, Dingding;  Yan, Qi;  Tong, Linjiang 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 5-(Methylthio)pyrimidine derivatives  Mutant selective inhibitors  Epidermal growth factor inhibitor  NSCLC  Structure-based drug design   Discovery of 1,3-Diaryl-pyridones as Potent VEGFR-2 Inhibitors: Design, Synthesis, and Biological Evaluation 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 87, 期号: 5, 页码: 694-703 作者:  Yan, Wei;  Huang, Zhaoru;  Wang, Zhengyu;  Cao, Sufen;  Tong, Linjiang 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 1  3-Diaryl-pyridone  angiogenesis  anticancer agent  Chan-Lam coupling  VEGFR-2 inhibitors   Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12 作者:  Xiao, Qiang;  Qu, Rong;  Gao, Dingding;  Yan, Qi;  Tong, Linjiang 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/06 5-(Methylthio)pyrimidine derivatives  Mutant selective inhibitors  Epidermal growth factor inhibitor  NSCLC  Structure-based drug design   dw10075anovelselectiveandsmallmoleculeinhibitorofvegfrexhibitsantitumoractivitiesbothinvitroandinvivo 期刊论文 actapharmacologicasinica, 2016, 卷号: 37, 期号: 3, 页码: 398 作者:  Ll Mengyuan;  Lv Yongcong;  Tong Linjiang;  Peng Ting;  Qu Rong 收藏  |  浏览/下载：6/0  |  提交时间：2020/07/01 DW10075  VEGF/VEGF receptor inhibitor  Antitumor  Angiogenesis  U87-MG human glioblastoma   designsynthesisandbiologicalevaluationofbiphenylureaderivativesasvegfr2kinaseinhibitorsii 期刊论文 chinesechemicalletters, 2016, 卷号: 27, 期号: 2, 页码: 200 作者:  Gao Guorui;  Li Mengyuan;  Lv Yongcong;  Cao Sufen;  Tong Linjiang 收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01 GROWTH-FACTOR RECEPTOR-2  POTENT  ANGIOGENESIS  DISCOVERY  SORAFENIB  TOXICITY  CANCER  Angiogenesis  Kinase  Inhibitor  VEGFR-2