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浏览/检索结果: 共15条，第1-10条 帮助 限定条件 发表日期：2016    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 124, 页码: 981-991 作者:  Ma, Guang-Hui;  Ye, Yan;  Zhang, Dan;  Xu, Xin;  Si, Pei 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 HFMD  EV71 3C(Pro)  Non-peptidyl inhibitor  Virtual screening   Agglutinin isolated from Arisema heterophyllum Blume induces apoptosis and autophagy in A549 cells through inhibiting PI3K/Akt pathway and inducing ER stress 期刊论文 CHINESE JOURNAL OF NATURAL MEDICINES, 2016, 卷号: 14, 期号: 11, 页码: 856-864 作者:  Feng Li-Xing;  Sun Peng;  Mi Tian;  Liu Miao;  Liu Wang 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 Agglutinin  Arisaema heterophyllum Blume  Human non-small-cell lung cancer A549 cell line  Apoptosis  Autophagy   Novel CHOP activator LGH00168 induces necroptosis in A549 human lung cancer cells via ROS-mediated ER stress and NF-kappa B inhibition 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1381-1390 作者:  Ma, Yi-ming;  Peng, Yan-min;  Zhu, Qiong-hua;  Gao, An-hui;  Chao, Bo 收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 CHOP  LGH00168  ER stress  NF-kappa B  necroptosis  RIP1  ROS  non-small cell lung cancer A549 cells  cancer xenograft mice   Bacillus as a potential diagnostic marker for yellow tongue coating 期刊论文 SCIENTIFIC REPORTS, 2016, 卷号: 6 作者:  Ye, Juan;  Cai, Xueting;  Yang, Jie;  Sun, Xiaoyan;  Hu, Chunping 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Trimer procyanidin oligomers contribute to the protective effects of cinnamon extracts on pancreatic beta-cells in vitro 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 8, 页码: 1083-1090 作者:  Sun, Peng;  Wang, Ting;  Chen, Lu;  Yu, Bang-wei;  Jia, Qi 收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 cinnamon  procyanidin oligomers  cinnamtannin B1  procyanidin C1  cinnamtannin D1  diabetes  pancreatic beta-cells  cultured murine islets  lipotoxicity  ROS  insulin secretion   Silibinin and indocyanine green-loaded nanoparticles inhibit the growth and metastasis of mammalian breast cancer cells in vitro 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 7, 页码: 941-949 作者:  Sun, Hui-ping;  Su, Jing-han;  Meng, Qing-shuo;  Yin, Qi;  Zhang, Zhi-wen 收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 breast cancer  4T1 mammalian breast cancer cells  metastasis  nanoparticles  silibinin  photothermal therapy  NIR laser irradiation   Structure-based optimization and derivatization of 2-substituted quinolone-based non-nucleoside HCV NS5B inhibitors with submicromolar cellular replicon potency 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 12, 页码: 2900-2906 作者:  Cheng, Yu;  Shen, Jian;  Peng, Run-Ze;  Wang, Gui-Feng;  Zuo, Jian-Ping 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 HCV NS5B polymerase  2-Alkyl quinolone  1,6-Naphthyridine-4,5-dione  Non-nucleoside inhibitor  Direct acting antiviral  Allosteric site   Chikusetsusaponin IVa Butyl Ester (CS-IVa-Be), a Novel IL6R Antagonist, Inhibits IL6/STAT3 Signaling Pathway and Induces Cancer Cell Apoptosis 期刊论文 MOLECULAR CANCER THERAPEUTICS, 2016, 卷号: 15, 期号: 6, 页码: 1190-1200 作者:  Yang, Jie;  Qian, Shihui;  Cai, Xueting;  Lu, Wuguang;  Hu, Chunping 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 Discovery of a new series of imidazo[1,2-a]pyridine compounds as selective c-Met inhibitors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 5, 页码: 698-707 作者:  Liu, Tong-chao;  Peng, Xia;  Ma, Yu-chi;  Ji, Yin-chun;  Chen, Dan-qi 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 c-Met inhibitors  hepatocyte growth factor receptor  imidazo[1,2-a]pyridine  anticancer agents  drug discovery   Novel analogues of diterpenoid alkaloids from ring distortion of talatisamine, a potassium ion channel blocker 期刊论文 TETRAHEDRON, 2016, 卷号: 72, 期号: 10, 页码: 1357-1363 作者:  Tang, Hua;  Chen, Qi-Feng;  Liu, Xiao-Yu;  Zhang, Hua;  Chen, Dong-Lin 收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 Diterpenoid alkaloid  Natural product  Ring distortion  Talatisamine