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中国医学科学院 北... [21]
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期刊论文 [19]
会议论文 [2]
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2019 [4]
2017 [4]
2016 [5]
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专题:中国医学科学院 北京协和医学院
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Nitidine chloride exerts anti-inflammatory action by targeting Topoisomerase I and enhancing IL-10 production
期刊论文
2019, 卷号: 148, 页码: 104368
作者:
Yang Niao
;
Yue Rongcai
;
Ma Jinzhu
;
Li Wencai
;
Zhao Zeng
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/01/03
Chelerythrine Chloride (PubChem CID: 72311)
DNA topoisomerase I inhibitor
Endotoxemia
Interleukin-10
Irinotecan hydrochloride (PubChem CID: 74990)
LY294002 (PubChem CID: 3973)
Lipopolysaccharide
MK-2206 (PubChem CID: 46930998)
Nitidine Chloride (PubChem CID: 25659)
Phosphatidylinositol 3-kinase/Akt pathway
SN-38 (PubChem CID: 104842)
Sanguinarine chloride (PubChem CID: 68635)
Topotecan hydrochloride (PubChem CID: 60699)
CMAB009 plus irinotecan versus irinotecan-only as second-line treatment after fluoropyrimidine and oxaliplatin failure in KRAS wild-type metastatic colorectal cancer patients: promising findings from a prospective, open-label, randomized, phase I
期刊论文
2019, 卷号: 39, 期号: 1, 页码: 28
作者:
Shi, Yuankai
;
Li, Jin
;
Xu, Jianming
;
Sun, Yan
;
Wang, Liwei
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/01/03
CMAB009
Cetuximab
Irinotecan
Second-line
mCRC
EGFR
KRAS
Immunogenicity
Fluoropyrimidine
Oxaliplatin failure
A validated UPLC-MS/MS method to determine free and total irinotecan and its two metabolites in human plasma after intravenous administration of irinotecan hydrochloride liposome injection
期刊论文
2019, 卷号: 170, 页码: 112-123
作者:
Zhuang, Quankun
;
Liu, Xuemei
;
Sun, Zhuo
;
Wang, Hongyun
;
Jiang, Ji
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/01/03
Free irinotecan
SN-38
SN-38G
UPLC-MS/MS
SPE
Irinotecan hydrochloride liposome injection
Irinotecan plus S-1 versus S-1 in patients with previously treated recurrent or metastatic esophageal cancer (ESWN 01): a prospective randomized, multicenter, open-labeled phase 3 trial
期刊论文
2019, 卷号: 39, 期号: 1, 页码: 16
作者:
Huang, Jing
;
Xu, Binghe
;
Liu, Ying
;
Huang, Junxing
;
Lu, Ping
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/01/03
Esophageal squamous cell carcinoma
Recurrent
Metastasis
Multicenter
open-label
randomized trial
Irinotecan
S-1
Overall survival
Progression-free survival
Objective response rate
Disease control rate
Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out sample pr
期刊论文
2017, 卷号: 7, 期号: 69, 页码: 43621-43635
作者:
Guan, Huanyu
;
Wang, Xiaoming
;
Wang, Shiping
;
He, Yang
;
Yue, Jiajing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity
期刊论文
2017, 卷号: 8, 页码: 769
作者:
Guan, Huan-yu
;
Li, Peng-fei
;
Wang, Xiao-ming
;
Yue, Jia-jing
;
He, Yang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/01/03
Shengjiang Xiexin decoction
irinotecan (CPT-11)
diarrhea
pharmacokinetics
UHPLC-MS/MS
A phase III trial (ZJBI0009): CMABOO9 plus irinotecan versus irinotecan alone as second-line treatment after fluoropyrimidine and oxaliplatin failure in wild-type K-ras metastatic colorectal cancer patients.
会议论文
JOURNAL OF CLINICAL ONCOLOGY, 2017-05-20
作者:
Shi, Yuankai
;
Li, Jin
;
Xu, Jianming
;
Cheng, Ying
;
Liu, Wei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
A phase III trial (ZJBI0009): CMABOO9 plus irinotecan versus irinotecan alone as second-line treatment after fluoropyrimidine and oxaliplatin failure in wild-type K-ras metastatic colorectal cancer patients.
期刊论文
2017, 卷号: 35
作者:
Shi, Yuankai
;
Li, Jin
;
Xu, Jianming
;
Cheng, Ying
;
Liu, Wei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Molecular Genetics External Quality Assessment Pilot Scheme for Irinotecan-Related UGT1A1 Genotyping in China
期刊论文
2016, 卷号: 11, 期号: 1
作者:
Yi, Lang
;
Lin, Guigao
;
Zhang, Kuo
;
Wang, Lunan
;
Zhang, Rui
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Irinotecan plus fluorouracil-based regimen as second or third-line chemotherapy for recurrent or metastatic esophageal squamous cell carcinoma
期刊论文
2016, 卷号: 7, 期号: 2, 页码: 246-250
作者:
Wang, Xi
;
Wang, Xinwei
;
Huang, Jing
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
5-Fluorouracil
chemotherapy
esophageal squamous cell carcinoma
irinotecan
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