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中国医学科学院 北... [33]
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期刊论文 [30]
会议论文 [3]
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2019 [7]
2018 [14]
2017 [6]
2016 [2]
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2013 [2]
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专题:中国医学科学院 北京协和医学院
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Melatonin alleviates cigarette smoke-induced endothelial cell pyroptosis through inhibiting ROS/NLRP3 axis
期刊论文
2019, 卷号: 519, 期号: 2, 页码: 402-408
作者:
Wang Xuebin
;
Bian Ye
;
Zhang Rui
;
Liu Xudong
;
Ni Leng
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
Cigarette smoke
Endothelial dysfunction
Melatonin
NLRP3 inflammasome
Pyroptosis
Icariin alleviates osteoarthritis by inhibiting NLRP3-mediated pyroptosis
期刊论文
2019, 卷号: 14, 期号: 1, 页码: 307
作者:
Zu Yan
;
Mu Yue
;
Li Qiang
;
Zhang Shu-Ting
;
Yan Hong-Juan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Caspase-1 signaling
Icariin
NLRP3 inflammasome
Osteoarthritis
Pyroptosis
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
期刊论文
2019, 卷号: 212, 页码: 36-53
作者:
Ai Q D
;
Chen Chen
;
Chu Shifeng
;
Zhang Zhao
;
Luo Yun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain
BCA = bicinchoninic acid
BSA = bovine serum albumin
CCA = common carotid artery
CCR4 = C-C chemokine receptor type 4
CKLF1 = chemokine-like factor 1
CO-IP = coimmunoprecipitation
ECA = external carotid artery
ELISA = enzyme-linked immunosorbent assay
FDA = Food and Drug Administration
I/R = ischemic/reperfusion
ICA = internal carotid artery
IL-18 = interleukin 18
IL-1β = interleukin 1β
LDH = lactate dehydrogenase
NLRP3 = NOD-like receptor protein 3
PBS = phosphate-buffered saline
SD = standard deviation
TNF-α = tumor necrosis factor α
TTC = 2
3
5-triphenyltetrazolium-chloride
WT = wild-type
pMCAO = permanent middle cerebral artery occlusion
pro-Caspase-1 = precursor Caspase-1
qPCR = quantitative real-time PCR
tMCAO = transient middle cerebral artery occlusion
tPA = tissue plasminogen activator
NLRP3 inflammasome pathway is involved in olfactory bulb pathological alteration induced by MPTP
期刊论文
2019, 卷号: 40, 期号: 8, 页码: 991-998
作者:
Chen, Ying
;
Zhang, Qiu-shuang
;
Shao, Qian-hang
;
Wang, Shuo
;
Yuan, Yu-he
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Parkinson's disease
olfactory bulb
alpha-synuclein
TLR4
NF-kappa B
NLRP3
neuroinflammation
MPTP
probenecid
The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinson's disease
期刊论文
2019, 卷号: 67, 页码: 458-464
作者:
Wang, Shuo
;
Yuan, Yu-He
;
Chen, Nai-Hong
;
Wang, Hong-Bo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
NLRP3 inflammasome
Pyroptosis
Neuroinflammation
Parkinson's disease
Interactions Between Enteroviruses and the Inflammasome: New Insights Into Viral Pathogenesis
期刊论文
2019, 卷号: 10, 页码: 321
作者:
Xiao, Xia
;
Qi, Jianli
;
Lei, Xiaobo
;
Wang, Jianwei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
enteroviruses
NLRP3 inflammasome
2B and 3D
2A and 3C
pathogenesis
Synthesis and Biological Evaluation of Fangchinoline Derivatives as Anti-Inflammatory Agents through Inactivation of Inflammasome
期刊论文
2019, 卷号: 24, 期号: 6
作者:
Liu, Ting
;
Zeng, Qingxuan
;
Zhao, Xiaoqiang
;
Wei, Wei
;
Li, Yinghong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
fangchinoline
Anti-inflammatory
IL-1
NLRP3 inflammasome
THE ANTI-INFLAMMATORY EFFECT OF R3 IN ATHEROSCLEROSIS IS ASSOCIATED WITH INHIBITION OF NLRP3 INFLAMMASOME
期刊论文
2018, 卷号: 275, 页码: E27-E27
作者:
Xu, Y.
;
Si, Sh. Y.
;
L, J. Q.
;
W, X.
;
Li, Y. Zh
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Delayed oseltamivir plus sirolimus treatment attenuates H1N1 virus-induced severe lung injury correlated with repressed NLRP3 inflammasome activation and inflammatory cell infiltration
期刊论文
2018, 卷号: 14, 期号: 11, 页码: e1007428
作者:
Jia, Xuehong
;
Liu, Bo
;
Bao, Linlin
;
Lv, Qi
;
Li, Fengdi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation
期刊论文
2018, 卷号: 9, 页码: 1346
作者:
Ye, Tianyuan
;
Meng, Xiangbao
;
Zhai, Yadong
;
Xie, Weijie
;
Wang, Ruiying
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
cognitive dysfunction
diabetes mellitus
NLRP3 inflammasome
endoplasmic reticulum stress
apoptosis
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