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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 专题：湖南中医药大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Structure-activity relationship investigation of coumarin-chalcone hybrids with diverse side-chains as acetylcholinesterase and butyrylcholinesterase inhibitors 期刊论文 MOLECULAR DIVERSITY, 2018, 卷号: 22, 期号: 4, 页码: 893-906 作者:  Kang, Lu;  Gao, Xiao-Hui;  Liu, Hao-Ran*;  Men, Xue;  Wu, Hong-Nian 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/27 Coumarin  Chalcone  Cholinesterase inhibitors  Structure-activity relationship  Tertiary amine group   Structure-activity relationship investigation of benzamide and picolinamide derivatives containing dimethylamine side chain as acetylcholinesterase inhibitors. 期刊论文 Journal of Enzyme Inhibition and Medicinal Chemistry, 2018, 卷号: 33, 期号: 1, 页码: 110-114 作者:  Gao, Xiao-hui;  Liu, Lin-bo;  Liu, Hao-ran*;  Tang, Jing-jing;  Kang, Lu 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/27 Alzheimer's disease  Cholinesterase inhibitors  benzamide  picolinamide  structure-activity relationship   Discovery of potent and selective acetylcholinesterase (AChE) inhibitors: acacetin 7-O-methyl ether Mannich base derivatives synthesised from easy access natural product naringin 期刊论文 Natural Product Research, 2018, 卷号: 32, 期号: 6, 页码: 743-747 作者:  Liu, Hao-ran;  Men, Xue;  Gao, Xiao-hui;  Liu, Lin-bo;  Fan, Hao-qun 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/27 Alzheimer's diseases  Mannich base  Naringin  acetylcholinesterase inhibitors  molecular docking   Tertiary amine derivatives of chlorochalcone as acetylcholinesterase (AChE) and buthylcholinesterase (BuChE) inhibitors: the influence of chlorine, alkyl amine side chain and alpha,beta-unsaturated ketone group. 期刊论文 Journal of Enzyme Inhibition and Medicinal Chemistry, 2017, 卷号: 32, 期号: 1, 页码: 146-152 作者:  Gao, Xiao-hui;  Zhou, Chao;  Liu, Hao-ran*;  Liu, Lin-bo;  Tang, Jing-jing 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/27 *Acetylcholinesterase inhibitors  *Alzheimer's disease  *chlorochalcones  *pyrazoline  *structure-activity relationship   Novel ferulic amide derivatives with tertiary amine side chain as acetylcholinesterase and butyrylcholinesterase inhibitors: The influence of carbon spacer length, alkylamine and aromatic group 期刊论文 European Journal of Medicinal Chemistry, 2017, 卷号: 126, 页码: 810-822 作者:  Liu, Haoran;  Liu, Linbo;  Gao, Xiaohui;  Liu, Yingzi*;  Xu, Wanjun 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/27 Acetylcholinesterases  Alzheimer's disease  Ferulic acid  Molecular docking  alpha,beta-Unsaturated carbonyl   Design, synthesis and preliminary structure-activity relationship investigation of nitrogen-containing chalcone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors: a further study based on Flavokawain B Mannich base derivatives. 期刊论文 Journal of Enzyme Inhibition and Medicinal Chemistry, 2016, 卷号: 31, 期号: 4, 页码: 580-589 作者:  Liu, Haoran*;  Fan, Haoqun;  Gao, Xiaohui;  Huang, Xueqing;  Liu, Xianjun 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/27 Acetylcholinesterase inhibitors  Alzheimer's disease  chalcones  structure-activity relationship   Novel Potent and Selective Acetylcholinesterase Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease: Synthesis, Pharmacological Evaluation, and Molecular Modeling of Amino-Alkyl-Substituted Fluoro-Chalcones Derivatives 期刊论文 Chemical Biology & Drug Design, 2015, 卷号: 86, 期号: 4, 页码: 517-522 作者:  Liu, Hao-Ran*;  Zhou, Chao;  Fan, Hao-Qun;  Tang, Jing-Jing;  Liu, Lin-Bo 收藏  |  浏览/下载：1/0  |  提交时间：2019/12/27 AChE inhibitors  chalcone  fluorine  molecular modeling  selectivity   Design, synthesis and pharmacological evaluation of chalcone derivatives as acetylcholinesterase inhibitors 期刊论文 Bioorganic and Medicinal Chemistry, 2014, 卷号: 22, 期号: 21, 页码: 6124-6133 作者:  Liu, Hao-ran*;  Liu, Xian-jun;  Fan, Hao-qun;  Tang, Jing-jing;  Gao, Xiao-hui 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/27 AD  Alzheimer’s disease  AChE  acetylcholinesterases  ACh  acetylcholine  BuChE  butyrylcholinesterase  PAS  peripheral anionic sites  Log P  octanol/water partition  CNS  central nervous system  BBB  blood brain barrier  Chalcone derivatives  AChE inhibitors  Log P  Molecular docking