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科研机构
复旦大学上海医学院 [32]
内容类型
期刊论文 [26]
会议论文 [6]
发表日期
2019 [3]
2018 [3]
2017 [1]
2016 [3]
2015 [7]
2014 [1]
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专题:复旦大学上海医学院
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Discovery, synthesis, biological evaluation and molecular docking study of (R)-5-methylmellein and its analogs as selective monoamine oxidase A inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 10
作者:
Lei, Xinsheng
;
Hu, Jin-Feng
;
Guan, Hui-Da
;
Wang, Chang-Hong
;
Huang, Chao
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/12/05
Natural product
5-Methylmellein
Synthetic analogs
Monoamine oxidase
Inhibitor
Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163
作者:
Li, Yali
;
Huang, Taomin
;
Lou, Bin
;
Ye, Deyong
;
Qi, Xiangyu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/05
Sphingomyelin synthase 2
Inhibitor
ApoE KO mice
Atherosclerosis
Design, synthesis, and bioactivities of tasiamide B derivatives as cathepsin D inhibitors
期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2019, 卷号: 25, 期号: 4
作者:
Zhang, Wei
;
Liu, Jian
;
Li, Zhi
;
Bao, Keting
;
Xu, Hao
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Ahppa
cathepsin D
selective inhibitor
tasiamide B derivatives
Preparation of carbon-functionalized magnetic graphene/mesoporous silica composites for selective extraction of miglitol and voglibose in rat plasma
期刊论文
TALANTA, 2018, 卷号: 182
作者:
Liu, Xiaodan
;
Feng, Jianan
;
Li, Yan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Magnetic graphene
Mesoporous silica composites
Carbon-functionalized
Restricted access matrix solid phase extraction (RAM-SPE)
alpha-glucosidase inhibitor
Preliminary Results from a Phase 1 Study of HMPL-523, a Highly Selective Syk Inhibitor, in Chinese Patients with Mature B-Cell Lymphomas
会议论文
作者:
Zhu, Jun
;
Cao, Junning
;
Qiu, Lugui
;
Qi, Junyuan
;
Song, Yuqin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
Phase III trial of chidamide, a subtype-selective histone deacetylase (HDAC) inhibitor, in combination with exemestane in patients with hormone receptor-positive advanced breast cancer
会议论文
作者:
Jiang, Z.
;
Li, W.
;
Hu, X.
;
Zhang, Q.
;
Sun, T.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Discovery of the selective sphingomyelin synthase 2 inhibitors with the novel structure of oxazolopyridine
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 15
作者:
Qi, Xiang-Yu
;
Cao, Yang
;
Li, Ya-Li
;
Mo, Ming-Guang
;
Zhou, Lu
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Sphingomyelin synthase 2
Anti-atherosclerosis
Oxazolopyridine
Selective inhibitor
Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 25
作者:
Wang, Ying
;
Zhan, Zhengsheng
;
Jiang, Xifei
;
Peng, Xia
;
Shen, Yanyan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/06
c-Met
kinase inhibitor
Simm530
A Phase I study of safety and pharmacokinetics of fruquintinib, a novel selective inhibitor of vascular endothelial growth factor receptor-1,-2, and-3 tyrosine kinases in Chinese patients with advanced solid tumors
期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2016, 卷号: 78, 期号: 2
作者:
Cao, Junning
;
Zhang, Jian
;
Peng, Wei
;
Chen, Zhiyu
;
Fan, Songhua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/06
Fruquintinib
Phase I study
VEGFR
Advanced solid tumors
Safety and pharmacokinetics
Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12
作者:
Xiao, Qiang
;
Qu, Rong
;
Gao, Dingding
;
Yan, Qi
;
Tong, Linjiang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/06
5-(Methylthio)pyrimidine derivatives
Mutant selective inhibitors
Epidermal growth factor inhibitor
NSCLC
Structure-based drug design
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