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科研机构
复旦大学上海医学院 [95]
内容类型
期刊论文 [89]
会议论文 [6]
发表日期
2019 [4]
2018 [9]
2017 [9]
2016 [7]
2015 [8]
2014 [10]
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Combining a Fusion Inhibitory Peptide Targeting the MERS-CoV S2 Protein HR1 Domain and a Neutralizing Antibody Specific for the S1 Protein Receptor-Binding Domain (RBD) Showed Potent Synergism against Pseudotyped MERS-CoV with or without Mutations in RBD
期刊论文
VIRUSES-BASEL, 2019, 卷号: 11, 期号: 1
作者:
Wang, Cong
;
Hua, Chen
;
Xia, Shuai
;
Li, Weihua
;
Lu, Lu
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/12/05
MERS-CoV
RBD
mutation
peptide
neutralizing antibody
combination
In Silico Identification of Novel Aromatic Compounds as Potential HIV-1 Entry Inhibitors Mimicking Cellular Receptor CD4
期刊论文
VIRUSES-BASEL, 2019, 卷号: 11, 期号: 8
作者:
Kornoushenko, Yuri V.
;
Tuzikov, Alexander V.
;
Jiang, Shibo
;
Andrianov, Alexander M.
;
Nikolaev, Grigory I.
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
HIV-1 gp120 protein
cellular receptor CD4
CD4-mimetics
virtual screening
in silico click chemistry
molecular docking
quantum chemical calculations
molecular dynamics simulations
binding free energy calculations
anti-HIV-1 drugs
Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10
作者:
Chen, Shuanghong
;
Lu, Mengjie
;
Liu, Dongsheng
;
Yang, Lingyun
;
Yi, Cuiying
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/05
Increased metabolic activity and hysteretic enhanced GABA(A) receptor binding in a rat model of salicylate-induced tinnitus
期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 364
作者:
Wu, Cong
;
Bao, Weiqi
;
Yi, Bin
;
Wang, Qixuan
;
Wu, Xu
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Tinnitus
Salicylate
Metabolic activity
GABA(A) receptor binding
Prospects for a MERS-CoV spike vaccine
期刊论文
EXPERT REVIEW OF VACCINES, 2018, 卷号: 17, 期号: 8
作者:
Zhou, Yusen
;
Jiang, Shibo
;
Du, Lanying
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
MERS
MERS-CoV
spike protein
receptor-binding domain
vaccine
immune responses
neutralizing antibodies
protection
NLRP3 inFLammasome mediates chronic intermittent hypoxia-induced renal injury implication of the microRNA-155/FOXO3a signaling pathway
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2018, 卷号: 233, 期号: 12
作者:
Wu, Xu
;
Chang, Su Chi
;
Jin, Jifu
;
Gu, Wenyu
;
Li, Shanqun
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
chronic intermittent hypoxia (CIH)
chronic renal injury
microRNA-155 (miR-155)
nucleotide-binding domain like receptor protein 3 (NLRP3) inflammasome
oxidative stress
Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150
作者:
Dal Maso, Emma
;
Zhu, Yue
;
Vi Pham
;
Reynolds, Christopher A.
;
Deganutti, Giuseppe
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
G protein-coupled receptor
Calcitonin receptor
GPCR structure-function
Biased agonism
Molecular modelling
Cholestasis-induced bile acid elevates estrogen level via farnesoid X receptor-mediated suppression of the estrogen sulfotransferase SULT1E1
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 33
作者:
Liu, Xijun
;
Xue, Ruyi
;
Yang, Caiting
;
Gu, Jianxin
;
Chen, She
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
acetylation
cAMP response element-binding protein (CREB)
estrogen receptor
bile acid
nuclear receptor
7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14
作者:
Sun, Hui-jiao
;
Wang, Yu-hua
;
Yuan, Cong-min
;
Kong, Ling-hui
;
Xu, Xue-jun
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
7 beta-Methyl-nepenthone analogues
KOR ligands
Concept of hybridization
Opioid receptor binding and functional activities
RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 52, 期号: 4
作者:
Qi, Zi-Hao
;
Xu, Hua-Xiang
;
Zhang, Shi-Rong
;
Xu, Jin-Zhi
;
Li, Shuo
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
pancreatic cancer
receptor-interacting protein kinase 4
RAF1
MEK
ERK pathway
phosphatidylethanolamine binding protein 1
tumor metastasis
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