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科研机构
复旦大学上海医学院 [15]
内容类型
期刊论文 [15]
发表日期
2014 [2]
2013 [1]
2012 [1]
2011 [4]
2010 [2]
2009 [1]
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专题:复旦大学上海医学院
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Optimization of the Antiviral Potency and Lipophilicity of Halogenated 2,6-Diarylpyridinamines as a Novel Class of HIV-1 NNRTIS
期刊论文
CHEMMEDCHEM, 2014, 卷号: 9, 期号: 7
作者:
Wu, Zhi-Yuan
;
Liu, Na
;
Qin, Bingjie
;
Huang, Li
;
Yu, Fei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
anti-HIV activity
antiviral agents
diarylpyridinamines
drug-like properties
lipophilicity
Physicochemical property-driven optimization of diarylaniline compounds as potent HIV-1 non-nucleoside reverse transcriptase inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 16
作者:
Liu, Na
;
Qin, Bingjie
;
Sun, Lian-Qi
;
Yu, Fei
;
Lu, Lu
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
Anti-HIV agents
Diarylaniline
NNRTIs
Physicochemical property
Small molecule fusion inhibitors: Design, synthesis and biological evaluation of (Z)-3-(5-(3-benzyl-4-oxo-2-thioxothiazolidinylidene)methyl)-N-(3-carboxy-4-hydroxy)phenyl-2,5-dimethylpyrroles and related derivatives targeting HIV-1 gp41
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 23
作者:
He, Xiao-Yang
;
Lu, Lu
;
Qiu, Jiayin
;
Zou, Peng
;
Yu, Fei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/19
3-Substituted N-(3-carboxy-4-hydroxy)phenyl-2,5-dimethylpyrrole derivatives
Small-molecule fusion inhibitors
HIV-1 gp41
Anti-HIV agents
L-Selectin and P-Selectin Are Novel Biomarkers of Cervicovaginal Inflammation for Preclinical Mucosal Safety Assessment of Anti-HIV-1 Microbicide
期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 卷号: 56, 期号: 6
作者:
Zhong, Maohua
;
He, Benxia
;
Yang, Jingyi
;
Bao, Rong
;
Zhang, Yan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/19
Synthesis and Anti-HIV Activity of Aryl-2-[(4-cyanophenyl)amino]-4-pyrimidinone hydrazones as Potent Non-nucleoside Reverse Transcriptase Inhibitors
期刊论文
CHEMMEDCHEM, 2011, 卷号: 6, 期号: 12
作者:
Ma, Xiao-Dong
;
Yang, Shi-Qiong
;
Gu, Shuang-Xi
;
He, Qiu-Qin
;
Chen, Fen-Er
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
antiviral agents
diarylpyrimidines
HIV-1
NNRTIs
reverse transcriptase
structure-activity relationships
Anti-AIDS agents 87. New bio-isosteric dicamphanoyl-dihydropyranochromone (DCP) and dicamphanoyl-khellactone (DCK) analogues with potent anti-HIV activity
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 卷号: 21, 期号: 19
作者:
Liu, Hong-Shan
;
Xu, Shi-Qing
;
Cheng, Ming
;
Chen, Ying
;
Xia, Peng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/19
2 '-Monomethyl-1 '-oxa-DCP
2 '-Monomethyl-1 '-thia-DCP
2-Ethyl-1 '-thia-DCP
4-Methyl-1 '-thia-DCK
Anti-HIV activity
Design, synthesis and biological evaluation of 3-substituted 2,5-dimethyl-N-(3-(1H-tetrazol-5-yl)phenyl)pyrroles as novel potential HIV-1 gp41 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 22
作者:
He, Xiao-Yang
;
Zou, Peng
;
Qiu, Jiayin
;
Hou, Ling
;
Jiang, Shibo
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
Small-molecule fusion inhibitors
3-Substituted 2,5-dimethyl-N-(3-tetrazol-5yl)phenyl)pyrrole derivatives
HIV-1 gp41
Anti-HIV agents
Anti-AIDS agents 86. Synthesis and anti-HIV evaluation of 2 ',3 '-seco-3 '-nor DCP and DCK analogues
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 卷号: 46, 期号: 10
作者:
Chen, Ying
;
Cheng, Ming
;
Liu, Fa-Qiang
;
Xia, Peng
;
Qian, Keduo
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
2 ',3 '-Seco-3 '-nor-DCPs
Anti-HIV activity
Structure-activity relationship (SAR)
Anti-AIDS agents 82: Synthesis of seco-(3 ' R,4 ' R)-3 ',4 '-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) derivatives as novel anti-HIV agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 卷号: 18, 期号: 12
作者:
Tang, Jian
;
Qian, Keduo
;
Zhang, Bei-Na
;
Chen, Ying
;
Xia, Peng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/19
Seco-DCK analogs
Anti-HIV agents
Anti-AIDS agents 84. Synthesis and anti-human immunodeficiency virus (HIV) activity of 2 '-monomethyl-4-methyl- and 1 '-thia-4-methyl-(3 ' R,4 ' R)-3 ',4 '-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) analogs
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 卷号: 18, 期号: 20
作者:
Xu, Shi-Qing
;
Yan, Xin
;
Chen, Ying
;
Xia, Peng
;
Qian, Keduo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
2 '-Monomethyl-4-methyl-(3 ' R,4 ' R)-3 ',4 '-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) analogs
1 '-Thia-4-methyl-(3 ' R,4 ' R)-3 ',4 '-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) analogs
Anti-HIV activity
Structure-activity relationship (SAR)
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