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科研机构
中南大学 [17]
内容类型
期刊论文 [17]
发表日期
2018 [2]
2017 [3]
2016 [5]
2015 [3]
2014 [1]
2012 [1]
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Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:
Han, Yachun
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/03
ALT
alanine aminotransferase
AST
aspartate aminotransferase
BUN
blood urea nitrogen
BW
body weight
BG
blood glucose
DCFDA
dichlorodihydrofluorescein diacetate
DN
diabetic nephropathy
ECL
enhanced chemiluminescence
EM
electron microscopy
EMT
epithelial–mesenchymal transition
HbA1C
hemoglobin A1c
HE
hematoxylin-eosin
IF
immunofluorescence
IHC
immunohistochemistry
KW
kidney weight
LDL
low-density lipoprotein
MDA
malondialdehyde
MFI
median fluorescence intensity
MMP
mitochondrial transmembrane potential
MMT
methyl methane-thiosulphonate
MPTP
mitochondrial permeability transition pore
MSU
monosodium urate
MtROS
mitochondria reactive oxygen species
PAS
periodic acid-Schiff
Scr
serum creatinine
TC
total cholesterol
TG
triglyceride
TBARS
thiobarbituric acid reactive substances
TPP
triphenylphosphonium
TRX
thioredoxin
TXNIP
thioredoxin-interacting protein
TUNEL
terminal deoxynucleotidyl transferase dUTP nick end-labeling
8-OHdG
8-oxo-deoxyguanosine
UA
uric acid
Diabetic nephropathy
Mitochondria
Reactive oxygen species (ROS)
TRX/TXNIP
NLRP3 inflammasome
MitoQ
MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury
期刊论文
The Journal of clinical investigation, 2018, 卷号: 128, 期号: 12, 页码: 5448-5464
作者:
Wei, Qingqing*
;
Sun, Haipeng
;
Song, Shuwei
;
Liu, Yong
;
Liu, Pengyuan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/03
Mitochondria
Nephrology
Noncoding RNAs
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Ginsenoside Rg3 attenuates sepsis-induced injury and mitochondrial dysfunction in liver via AMPK-mediated autophagy flux
期刊论文
Bioscience Reports, 2017, 卷号: 37, 期号: 4
作者:
Xing, Wei
;
Yang, Lei
;
Peng, Yue
;
Wang, Qianlu
;
Gao, Min
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Autophagy
Liver injury
Mitochondrial dysfunction
Rg3
Sepsis
Mitochondria: A Novel Therapeutic Target in Diabetic Nephropathy.
期刊论文
Current medicinal chemistry, 2017, 卷号: 24, 期号: 29, 页码: 3185-3202
作者:
Yang, Shikun
;
Han, Yachun
;
Liu, Jun
;
Song, Panai
;
Xu, Xiaoxuan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
Diabetic nephropathy
Mitochondria
Renal injury
microvascular complications
mitochondrial dysfuction
mitophagy
Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 34403
作者:
Gao, Huimin
;
Chen, Zhaoyu
;
Fu, Yongmei
;
Yang, Xiaoyan
;
Weng, Ruihui
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Adeno-associated virus mediated SOD gene therapy protects the retinal ganglion cells from chronic intraocular pressure elevation induced injury via attenuating oxidative stress and improving mitochondrial dysfunction in a rat model
期刊论文
American Journal of Translational Research, 2016, 卷号: 8, 期号: 2, 页码: 799-810
作者:
Jiang, Wenmin
;
Tang, Luosheng
;
Zeng, Jun
;
Chen, Baihua*
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/03
Chronic intraocular pressure
SOD
retinal ganglion cells
Decreased expression of mitochondrial aldehyde dehydrogenase‐2 induces liver injury via activation of the mitogen‐activated protein kinase pathway
期刊论文
Transplant International, 2016, 卷号: 29, 期号: 1, 页码: 98-107
作者:
Zhong, Zibiao
;
Ye, Shaojun
;
Xiong, Yan
;
Wu, Lianxi
;
Zhang, Meng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
apoptosis
brain death
mitochondrial aldehyde dehydrogenase 2
mitogen‐activated protein kinase pathway
Sevoflurane Post-conditioning Enhanced Hippocampal Neuron Resistance to Global Cerebral Ischemia Induced by Cardiac Arrest in Rats through PI3K/Akt Survival Pathway.
期刊论文
FRONTIERS IN CELLULAR NEUROSCIENCE, 2016, 卷号: 10, 期号: NOV2016, 页码: 271
作者:
Wang, Zhihua
;
Ye, Zhi*
;
Huang, Guoding
;
Wang, Na
;
Wang, E.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
PI3K/Akt
global cerebral ischemic injury
mitochondrial biogenesis
post-conditioning
sevoflurane
Renoprotective approaches and strategies in acute kidney injury
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 163, 页码: 58-73
作者:
Yang, Yuan
;
Song, Meifang
;
Liu, Yu
;
Liu, Hong
;
Sun, Lin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
ACTH
Adrenocorticotropic hormone
AIF
Apoptosis inducing factor
AKI
Acute kidney injury
BMSC
Bone marrow derived stem cells
CIN
Contrast-induced nephropathy
COMP-Ang1
Cartilage oligomeric matrix protein-angiopoietin-1
CysLT1R
Cysteinyl leukotriene-1 receptor
DMARD
Disease-modifying antirheumatic drugs
eNOS
Endothelial nitric oxide synthase
eEPCs
Endothelial progenitor cells
HDAC
Histone deacetylase
HSPC
Hematopoietic stem and progenitor cells
IRI
Ischemia–reperfusion injury
ICAM-1
Intercellular adhesion molecule-1
JNK
c-Jun N-terminal kinase
KIF3B
Kinesin family member 3B
KIM-1
Kidney injury molecule 1
MAPK
Mitogen-activated protein kinase
MCP-1
Monocyte chemotactic protein-1
α-MSH
Alpha-melanocyte-stimulating hormone
MFG-E8
Milk fat globule-epidermal growth factor-factor VIII
MPT
Mitochondrial permeability transition
MSCs
Mesenchymal stem cells
NGAL
Neutrophil gelatinase-associated lipocalin
MDM2
Murine double minute-2
MMP-2
Matrix metallopeptidase 2
mTOR
Mammalian target of rapamycin
PI3K
Phosphatidylinositol-3 kinase
PACAP
Pituitary adenylate cyclase activating polypeptide
RAAS
Renin–angiotensin–aldosterone system
RANTES
Regulated upon activation normal T-cell expressed and secreted
RIP1
Receptor-interacting protein 1
TNF-α
Tumor necrosis factor-alpha
TWEAK
TNF-like weak inducer of apoptosis
VDRA
Vitamin D receptor agonist
Acute kidney injury
Kidney protection
Kidney repair
Renoprotection
Ischemia–reperfusion
Nephrotoxicity
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