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科研机构
山东大学 [33]
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期刊论文 [33]
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2019 [5]
2018 [8]
2017 [3]
2016 [4]
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专题:山东大学
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Inhibitory effects of polyphyllins I and VII on human cisplatin-resistant NSCLC via p53 upregulation and CIP2A/AKT/mTOR signaling axis inhibition
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 10, 页码: 768-777
作者:
Feng Fei-Fei
;
Cheng Peng
;
Sun Chao
;
Wang Hui
;
Wang Wei
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Polyphyllin I
Polyphyllin VII
Cisplatin-resistance
Non-small cell
lung cancer
p53
Cancerous inhibitor of protein phosphatase 2A
Akt/mTOR-Mediated Autophagy Confers Resistance To BET Inhibitor JQ1 In Ovarian Cancer
期刊论文
ONCOTARGETS AND THERAPY, 2019, 卷号: 12, 页码: 8063-8074
作者:
Luan, Wenqing
;
Pang, Yingxin
;
Li, Rui
;
Wei, Xuan
;
Jiao, Xiaoxiao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/11
BET inhibitor
ovarian cancer
drug resistance
autophagy
Akt/mTOR
pathway
Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties
期刊论文
Investigational New Drugs, 2019
作者:
Wu J.-D.
;
Cui Y.-J.
;
Zhou Y.-G.
;
Tang L.-Q.
;
Zhang C.-M.
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
Hepatocellular carcinoma
Liver microsome stability
Multidrug-resistance
Pharmacokinetics
Tubulin polymerization inhibitor
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice
期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
作者:
Li, Chao
;
Luo, Jiao
;
Guo, Shuju
;
Jia, Xiaoling
;
Guo, Chuanlong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
type 2 diabetes mellitus
protein tyrosine phosphatase 1B
insulin
resistance
hypoglycemic activity
dyslipidemia
Design, synthesis and evaluation of a series of 5-methoxy-2,3-naphthalimide derivatives as AcrB inhibitors for the reversal of bacterial resistance
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 7, 页码: 882-889
作者:
Jin, Chaobin
;
Alenazy, Rawaf
;
Wang, Yinhu
;
Mowla, Rumana
;
Qin, Yinhui
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
5-Methoxy-2,3-naphthalimide
Antimicrobial resistance
Efflux pump
inhibitor
AcrB
Synergism
Inhibition of efflux
Design, synthesis and biological activity evaluation of novel 4-subtituted 2-naphthamide derivatives as AcrB inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 143, 页码: 699-709
作者:
Wang, Yinhu
;
Mowla, Rumana
;
Ji, Shengli
;
Guo, Liwei
;
Lopes, Miguel A. De Barros
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
2-Naphthamide
Antibiotic resistance
Drug efflux
Efflux pump inhibitor
Histone deacetylase 6 inhibitor enhances resistance to Mycobacterium tuberculosis infection through innate and adaptive immunity in mice
期刊论文
PATHOGENS AND DISEASE, 2018, 卷号: 76, 期号: 6
作者:
Wang, Xiaolei
;
Tang, Xiaowei
;
Zhou, Zheng
;
Huang, Qing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
pulmonary mycobacterial infection
immune response
IL-10
HDAC6
inflammation
The BET-bromodomain inhibitor JQ1 mitigates vemurafenib drug resistance in melanoma
期刊论文
MELANOMA RESEARCH, 2018, 卷号: 28, 期号: 6, 页码: 521-526
作者:
Zhao, Bei
;
Cheng, Xiankui
;
Zhou, Xiyuan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
BET inhibitor
BRAF inhibitor
cancer drug resistance
melanoma
Transcription activated p73-modulated cyclin D1 expression leads to doxorubicin resistance in gastric cancer
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 15, 期号: 2, 页码: 1831-1838
作者:
Ji, Zhi-Peng
;
Qiang, Ling
;
Zhang, Jian-Liang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
cyclin D1
transcription activated p73
cyclin-dependent kinase 4
inhibitor
gastric cancer
Investigating Novel Resistance Mechanisms to Third-Generation EGFR Tyrosine Kinase Inhibitor Osimertinib in Non-Small Cell Lung Cancer Patients
期刊论文
CLINICAL CANCER RESEARCH, 2018, 卷号: 24, 期号: 13, 页码: 3097-3107
作者:
Yang, Zhe
;
Yang, Nong
;
Ou, Qiuxiang
;
Xiang, Yi
;
Jiang, Tao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
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