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科研机构
山东大学 [239]
内容类型
期刊论文 [239]
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2019 [38]
2018 [26]
2017 [21]
2016 [29]
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浏览/检索结果:
共239条,第1-10条
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专题:山东大学
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Tetramethylpyrazine attenuated bupivacaine-induced neurotoxicity in SH-SY5Y cells through regulating apoptosis, autophagy and oxidative damage
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 1187-1196
作者:
Wang, Shouliang
;
Xia, Bin
;
Qiao, Zonglei
;
Duan, Lian
;
Wang, Gongming
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
tetramethylpyrazine
bupivacaine
neurotoxicity
human neuroblastoma
cell
Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 3, 页码: 447-456
作者:
Wang, Zhao
;
Yu, Zhao
;
Kang, Dongwei
;
Zhang, Jian
;
Tian, Ye
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
HIV-1
NNRTIs
Doravirine
Acetamide
Prodrug
Drug design
Neuroprotective potential of ketamine prevents developing brain structure impairment and alteration of neurocognitive function induced via isoflurane through the PI3K/AKT/GSK-3 beta pathway
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 501-512
作者:
Wang, Ruiwei
;
Zhang, Zihao
;
Kumar, Mukesh
;
Xu, Guangming
;
Zhang, Mengyuan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
ketamine
isoflurane
neuroinflammatory
PI3K/AKT/GSK-3 beta pathway
cognitive impairment
Safety and sedative effect of intranasal dexmedetomidine in mandibular third molar surgery: a systematic review and meta-analysis
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 1301-1310
作者:
Liu, Shaopeng
;
Wang, Ye
;
Zhu, Yong
;
Yu, Tingting
;
Zhao, Huaqiang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
intranasal dexmedetomidine
sedation
mandibular third molar
meta-analysis
SAR study on inhibitors of GIIA secreted phospholipase A(2) using machine learning methods
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 5, 页码: 666-684
作者:
Zhang, Shengde
;
Li, Yang
;
Qin, Zijian
;
Tu, Guipin
;
Chen, Guang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
classification models
decision tree (DT)
GIIA sPLA(2) inhibitors
random forest (RF)
support vector machine (SVM)
Contemporary medicinal-chemistry strategies for discovery of blood coagulation factor Xa inhibitors
期刊论文
Expert Opinion on Drug Discovery, 2019, 卷号: 14, 期号: 9, 页码: 915-931
作者:
Hao X.
;
Zuo X.
;
Kang D.
;
Zhang J.
;
Song Y.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
anticoagulants
drug design
FXa
medicinal chemistry strategies
synthetic inhibitors
Indole: A privileged scaffold for the design of anti-cancer agents
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: 183
作者:
Wan Y.
;
Li Y.
;
Yan C.
;
Yan M.
;
Tang Z.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Anti-Cancer
Drug design
Indole
Structure-activity relationships
Study on TCM prescription target prediction based on literature
期刊论文
Proceedings - 2019 IEEE/WIC/ACM International Conference on Web Intelligence Workshops, WI 2019 Companion, 2019, 页码: 154-158
作者:
Qi, Xingliang
;
Zhou, Yang
;
Zhang, Zhuo
;
Chen, Cong
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
Drug targets
Research design
Traditional Chinese
Carvedilol attenuates carbon tetrachloride-induced liver fibrosis and hepatic sinusoidal capillarization in mice
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 2667-2676
作者:
Wu, Ying
;
Li, Zhen
;
Xiu, Ai-Yuan
;
Meng, Dong-Xiao
;
Wang, Si-Ning
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
carvedilol
liver fibrosis
hepatic sinusoid
angiogenesis
hepatic
stellate cell
mice
Erythropoietin enhances osteogenic differentiation of human periodontal ligament stem cells via Wnt/beta-catenin signaling pathway
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 2543-2552
作者:
Zheng, De-Hua
;
Wang, Xu-Xia
;
Ma, Dan
;
Zhang, Li-Na
;
Qiao, Qing-Fang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
erythropoietin
periodontal ligament stem cell
osteogenesis
Wnt/beta-catenin
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