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科研机构
过程工程研究所 [42]
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期刊论文 [35]
学位论文 [7]
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2021 [3]
2020 [12]
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Cost-effective purification process development for chimeric hepatitis B core (HBc) virus-like particles assisted by molecular dynamic simulation
期刊论文
ENGINEERING IN LIFE SCIENCES, 2021, 页码: 15
作者:
Zhang, Bingyang
;
Yin, Shuang
;
Wang, Yingli
;
Su, Zhiguo
;
Bi, Jingxiu
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/08/31
hepatitis B core
molecular dynamic simulation
protein characterization
protein purification
virus‐
like particle
Performance of agarose and gigaporous chromatographic media as function of pore-to-adsorbate size ratio over wide span from ovalbumin to virus like particles
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1638, 页码: 12
作者:
Yang, Yanli
;
Yu, Mengran
;
Ma, Guanghui
;
Su, Zhiguo
;
Zhang, Songping
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/03/29
Pore size
Protein size
Ion-exchange media
Ratio of pore-to-adsorbate size
Adsorption capacity
Adsorption kinetics
In vitro preparation of uniform and nucleic acid free hepatitis B core particles through an optimized disassembly-purification-reassembly process
期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 178, 页码: 7
作者:
Zhang, Yao
;
Liu, Yongdong
;
Zhang, Bingyang
;
Yin, Shuang
;
Li, Xiunan
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/08/31
Hepatitis B core (HBc)
Uniform VLPs
Nucleic acid removal
Disassembly-purification-reassembly
A novel multiple emulsion enhanced immunityviaits biomimetic delivery approach
期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2020, 卷号: 8, 期号: 33, 页码: 7365-7374
作者:
Zou, Yongjuan
;
Wu, Nan
;
Miao, Chunyu
;
Yue, Hua
;
Wu, Jie
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/10/30
Biosynthesis of Self-Assembled Proteinaceous Nanoparticles for Vaccination
期刊论文
ADVANCED MATERIALS, 2020, 页码: 13
作者:
Pan, Chao
;
Wu, Jun
;
Qing, Shuang
;
Zhang, Xiao
;
Zhang, Lulu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/10/30
AB(5)toxins
biosynthesis
conjugate vaccines
nanovaccines
self-assembled proteins
A biomimetic VLP influenza vaccine with interior NP/exterior M2e antigens constructed through a temperature shift-based encapsulation strategy
期刊论文
VACCINE, 2020, 卷号: 38, 期号: 38, 页码: 5987-5996
作者:
Wei, Jiangxue
;
Li, Zhengjun
;
Yang, Yanli
;
Ma, Xiaowei
;
An, Wenqi
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/10/30
Influenza Vaccine
Virus Like-particles
Biomimetic
Nucleoprotein
M2e
A Novel Particulate Delivery System Based on Antigen-Zn2+ Coordination Interactions Enhances Stability and Cellular Immune Response of Inactivated Foot and Mouth Disease Virus Shuai
期刊论文
MOLECULAR PHARMACEUTICS, 2020, 卷号: 17, 期号: 8, 页码: 2952-2963
作者:
Li, Shuai
;
Yang, Yanli
;
Lin, Xuan
;
Li, Zhengjun
;
Ma, Guanghui
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/09/22
Chitosan Particles
Coordination Binding
Foot And Mouth Disease Virus
Thermal Stability
Cellular Immunity
A novel rapid modularized hepatitis B core virus-like particle-based platform for personalized cancer vaccine preparation via fixed-point coupling
期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 28, 页码: 13
作者:
Ji, Mei
;
Zhu, Jie
;
Xie, Xi-xiu
;
Liu, Dong-qun
;
Wang, Bin
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/10/30
Hepatitis b Core Protein
Virus-like Particle (Vlp)
Personalized Cancer Vaccine
Spycatcher/spytag
t Cell Epitope
Characterization and stabilization in process development and product formulation for super large proteinaceous particles
期刊论文
ENGINEERING IN LIFE SCIENCES, 2020, 页码: 15
作者:
Yang, Yanli
;
Su, Zhiguo
;
Ma, Guanghui
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/09/22
characterization
denaturation
rational design
super large proteinaceous particles
以病毒样颗粒为“底盘”的流感疫苗仿生合成
学位论文
: 中国科学院大学, 2020
作者:
魏江雪
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/09/07
流感疫苗,病毒样颗粒,仿生合成,疫苗合成学,加热装载
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