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科研机构
大连化学物理研究所 [19]
内容类型
期刊论文 [17]
会议论文 [2]
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2019 [2]
2016 [3]
2015 [5]
2014 [5]
2011 [1]
2010 [3]
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物理化学 [5]
分析化学 [1]
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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
作者:
Ma, Hong-Ping
;
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/06/20
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
Cytochrome p450 3a enzymes are key contributors for hepatic metabolism of bufotalin, a natural constitute in chinese medicine chansu
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 10
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/05/08
Bufotalin
Cytochrome p450 3a (cyp3a)
Hydroxylation
Human liver microsomes (hlms)
Docking simulations
Separation and characterization of bufadienolides in toad skin using two-dimensional normal-phase liquid chromatography x reversed-phase liquid chromatography coupled with mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1026, 页码: 67-74
作者:
Zhang, Yun
;
Jin, Hongli
;
Li, Xiaolong
;
Zhao, Jianqiang
;
Guo, Xiujie
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/06/20
Bufadienolides
Normal-phase Liquid Chromatography
Two-dimensional Liquid Chromatography
Ms/ms
Toad Skin
Anti-gastric cancer activity in three-dimensional tumor spheroids of bufadienolides
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:
Zhang, Yun
;
Hou, Tao
;
Wei, Lai
;
Wang, Jixia
;
Zhang, Xiuli
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/06/20
Characterization of regio- and stereo-selective sulfation of bufadienolides: exploring the mechanism and providing insight into the structure-sulfation relationship by experimentation and molecular docking analysis
期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 7, 页码: 5774-5783
作者:
Ning, Jing
;
Cui, Yonglei
;
Wang, Chao
;
Dong, Peipei
;
Ge, Guangbo
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/06/20
psi-Bufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling
期刊论文
oncotarget, 2015, 卷号: 6, 期号: 13, 页码: 11627-11639
作者:
Ding, Jin
;
Wen, Wen
;
Xiang, Daimin
;
Yin, Peipei
;
Liu, Yanfang
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2015/11/17
psi-Bufarenogin
hepatocellular carcinoma
epithelial growth factor receptor
hepatocyte growth factor receptor
Characterization of Phase I Metabolism of Resibufogenin and Evaluation of the Metabolic Effects on Its Antitumor Activity and Toxicity
期刊论文
drug metabolism and disposition, 2015, 卷号: 43, 期号: 3, 页码: 299-308
作者:
Ning, Jing
;
Yu, Zhen-Long
;
Hu, Liang-Hai
;
Wang, Chao
;
Huo, Xiao-Kui
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/11/17
Pharmacokinetics and tissue distribution of five bufadienolides from the Shexiang Baoxin pill following oral administration to mice
期刊论文
journal of ethnopharmacology, 2015, 卷号: 161, 页码: 175-185
作者:
Huang, Huimei
;
Yang, Yongge
;
Lv, Chao
;
Chang, Wanlin
;
Peng, Chengcheng
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2015/11/17
Bufadienolides
Shexiang Baoxin Pill
Pharmacokinetic
Tissue distribution
LC-ESI-MS/MS
Interspecies variation in phase I metabolism of bufalin in hepatic microsomes from mouse, rat, dog, minipig, monkey, and human
期刊论文
XENOBIOTICA, 2015, 卷号: 45, 期号: 11, 页码: 954-960
作者:
Dai, Zi-Ru
;
Yang, Ling
;
Zou, Li-Wei
;
Li, Wei
;
Ma, Xiao-Chi
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/06/20
3-oxidation
5 Beta-hydroxylation
Bufalin
Cytochrome P450 3a
Species Differences
Preparative separation of a challenging anthocyanin from Lycium ruthenicum Murr. by two-dimensional reversed-phase liquid chromatography/hydrophilic interaction chromatography
期刊论文
rsc advances, 2015, 卷号: 5, 期号: 76, 页码: 62134-62141
作者:
Jin, Hongli
;
Zhao, Jianqiang
;
Zhou, Weijia
;
Shen, Aijin
;
Yang, Fan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2015/11/17
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