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科研机构
上海药物研究所 [27]
内容类型
期刊论文 [25]
会议论文 [2]
发表日期
2021 [3]
2019 [2]
2018 [2]
2017 [1]
2016 [1]
2015 [4]
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A novel low systemic diacylglycerol acyltransferase 1 inhibitor, Yhhu2407, improves lipid metabolism
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 卷号: 158, 页码: 9
作者:
Huang, Jun-Shang
;
Guo, Bin-Bin
;
Lin, Fei-Fei
;
Zeng, Li-Min
;
Wang, Ting
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
DGAT1
Inhibitor
Pharmacokinetics
Dyslipidemia
Lipid metabolism
NOD-like receptors in autoimmune diseases
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 15
作者:
Chen, Li
;
Cao, Shi-qi
;
Lin, Ze-min
;
He, Shi-jun
;
Zuo, Jian-ping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
pattern recognition receptors
NOD-like receptors
autoimmune diseases
inflammasomes
inhibitors
botanicals
DZ2002 alleviates psoriasis-like skin lesions via differentially regulating methylation of GATA3 and LCN2 promoters
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 91, 页码: 12
作者:
Chen, Li
;
Lin, Zemin
;
Liu, Yuting
;
Cao, Shiqi
;
Huang, Yueteng
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/05/24
DZ2002
Psoriasis
DNA methylation
Keratinocyte
Inflammatory infiltration
Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas
期刊论文
BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13
作者:
Zhang, Qing
;
Liu, Jian-He
;
Liu, Jing-Li
;
Qi, Chun-Ting
;
Yan, Lei
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/07/01
Receptor tyrosine kinases (RTKs)
Activation and function
Clear cell renal cell carcinomas (ccRCCs)
Targeted therapy
PDGFR beta
Stroma cells
Determining the protective effects of Yin-Chen-Hao Tang against acute liver injury induced by carbon tetrachloride using 16S rRNA gene sequencing and LC/MS-based metabolomics
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 174, 页码: 567-577
作者:
Liu, Fang
;
Sun, Zhaolin
;
Hu, Pei
;
Tian, Qiang
;
Xu, Zhou
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Yin-Chen-Hao Tang
Liver injury
Metabolomics
Gut microbiota
LC-MS
Gene sequencing
The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine
期刊论文
MOLECULAR GENETICS AND METABOLISM REPORTS, 2018, 卷号: 17, 页码: 46-52
作者:
Li, Hong
;
Zhao, Lihua
;
Singh, Rani
;
Ham, J. Nina
;
Fadoju, Doris O.
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2019/01/08
Glucagon receptor
Newborn screening
GCGR mutation
Hyperaminoacidemia
Mahvash disease
Pancreatic alpha cell hyperplasia (ACH)
Pancreatic neuroendocrine tumor (PNET)
FBW7 is associated with prognosis, inhibits malignancies and enhances temozolomide sensitivity in glioblastoma cells
期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 4, 页码: 1001-1011
作者:
Lin, Jing
;
Ji, Aihui
;
Qiu, Guanzhong
;
Feng, Huaizhi
;
Li, Jian
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Aurora B
FBW7
glioma
Mcl1
temozolomide
The long persistence of pyrrolizidine alkaloid-derived DNA adducts in vivo: kinetic study following single and multiple exposures in male ICR mice
期刊论文
Archives of toxicology, 2017, 卷号: 91, 期号: 2, 页码: 949-965
作者:
Zhu, Lin
;
Xue, Junyi
;
Xia, Qingsu
;
Fu, Peter P
;
Lin, Ge
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Receptor Tyrosine Kinase Phosphorylation Pattern-Based Multidrug Combination Is an Effective Approach for Personalized Cancer Treatment
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2016, 卷号: 15, 期号: 10, 页码: 2508-2520
作者:
Sun, Xiaoxiao
;
Song, Qiaoling
;
He, Li
;
Yan, Lei
;
Liu, Jingli
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Toll-like receptors: potential targets for lupus treatment
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 12, 页码: 1395-1407
作者:
Wu, Yan-wei
;
Tang, Wei
;
Zuo, Jian-ping
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
systemic lupus erythematosus
autoimmune diseases
Toll-like receptors
TLR antagonists
immune modulatory oligonucleotides
small molecular inhibitors
antibodies
miRNAs
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