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Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua
收藏  |  浏览/下载:35/0  |  提交时间:2021/11/04
Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:  Zhang, Hui;  Chen, Kun;  Tan, Qiuxiang;  Shao, Qiang;  Han, Shuo
收藏  |  浏览/下载:45/0  |  提交时间:2021/08/17
Identification of novel anti-inflammatory Nur77 modulators by virtual screening 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7
作者:  Ding, Xiaoyu;  Zhao, Zijie;  Wu, Yue;  Zhang, Hao;  Chen, Kaixian
收藏  |  浏览/下载:45/0  |  提交时间:2021/08/17
Insight into chemical basis of traditional Chinese medicine based on the state-of-the-art techniques of liquid chromatography-mass spectrometry 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1469-1492
作者:  Yu, Yang;  Yao, Changliang;  Guo, De-an
收藏  |  浏览/下载:41/0  |  提交时间:2021/08/17
Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition 期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936
作者:  Gao, Jing;  Zhang, Hanwu;  Zhou, Fengqi;  Hou, Bo;  Chen, Meiwan
收藏  |  浏览/下载:17/0  |  提交时间:2021/08/17
Diversity-oriented synthesis of cembranoid derivatives as potential anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 111, 页码: 8
作者:  Zhang, Cong;  Li, Heng;  Liu, Jin;  Liu, Moting;  Zhang, Hao
收藏  |  浏览/下载:25/0  |  提交时间:2021/08/17
Structural insights into the human D1 and D2 dopamine receptor signaling complexes 期刊论文
CELL, 2021, 卷号: 184, 期号: 4, 页码: 931-+
作者:  Zhuang, Youwen;  Xu, Peiyu;  Mao, Chunyou;  Wang, Lei;  Krumm, Brian
收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24
Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020, 卷号: 83, 期号: 12, 页码: 3536-3544
作者:  Zhang, Xianjing;  Li, Huihui;  Wang, Wenqiong;  Chen, Tong;  Xuan, Lijiang
收藏  |  浏览/下载:14/0  |  提交时间:2021/05/24
Molecular mechanisms of fentanyl mediated beta-arrestin biased signaling 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 4, 页码: 24
作者:  de Waal, Parker W.;  Shi, Jingjing;  You, Erli;  Wang, Xiaoxi;  Melcher, Karsten
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/01
Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 7, 页码: 15
作者:  Zhao, Shuang;  Zhu, Yan-Yan;  Wang, Xiao-Yu;  Liu, Yong-Sheng;  Sun, Yun-Xiang
收藏  |  浏览/下载:30/0  |  提交时间:2020/07/01


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