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科研机构
上海药物研究所 [18]
内容类型
期刊论文 [18]
发表日期
2021 [1]
2020 [2]
2019 [1]
2018 [2]
2017 [2]
2016 [1]
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Oncology [3]
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Engineering Oxaliplatin Prodrug Nanoparticles for Second Near-Infrared Fluorescence Imaging-Guided Immunotherapy of Colorectal Cancer
期刊论文
SMALL, 2021, 卷号: 17, 期号: 13, 页码: 11
作者:
Zhu, Qiurong
;
Sun, Fang
;
Li, Tianliang
;
Zhou, Mengxue
;
Ye, Jiayi
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2021/05/24
colorectal cancer
combinatory immunotherapy
immunogenic cell death
prodrug nanoparticles
second near‐
infrared fluorescence imaging
Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
He, Zhi-di
;
Zhang, Meng
;
Wang, Yong-hui
;
He, Yang
;
Wang, Hai-rui
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
tumor-targeted delivery
immunogenic cell death
PD-1
PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint
Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors
期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+
作者:
Li, Huiping
;
Liu, Rongrui
;
Shao, Bin
;
Ran, Ran
;
Song, Guohong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
Phase I
PARP inhibitor (fluzoparib)
solid tumor
pharmacokinetics
safety
antitumor activity
Phosphorylation of LIFR promotes prostate cancer progression by activating the AKT pathway
期刊论文
CANCER LETTERS, 2019, 卷号: 451, 页码: 110-121
作者:
Shao, Jialiang
;
Zhu, Wencheng
;
Ding, Yufeng
;
Zhu, Hongwen
;
Jing, Xiaoqian
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
LIFR
Phosphorylation
Prostate cancer
AKT
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:
Zhang, Ning
;
Yu, Zhimei
;
Yang, Xiaohong
;
Zhou, Yan
;
Tang, Qing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Proliferation
Anticancer drug
Phosphatidylinositol 3-kinase inhibitor
Apoptosis
Structure-activity relationship
Light-Activated Core-Shell Nanoparticles for Spatiotemporally Specific Treatment of Metastatic Triple-Negative Breast Cancer
期刊论文
ACS NANO, 2018, 卷号: 12, 期号: 3, 页码: 2789-2802
作者:
Meng, Qingshuo
;
Meng, Jia
;
Ran, Wei
;
Wang, Junyang
;
Zhai, Yihui
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
spatiotemporal
metastasis
triple-negative breast cancer
depth
photodynamic
Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase
期刊论文
CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 期号: 20, 页码: 6267-6278
作者:
Dai, Xiaoyang
;
Yan, Juan
;
Fu, Xuhong
;
Pan, Qiuming
;
Sun, Danni
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation
期刊论文
CELL RESEARCH, 2017, 卷号: 27, 期号: 6, 页码: 784-800
作者:
Lian, Qiaoshi
;
Xu, Jun
;
Yan, Shanshan
;
Huang, Min
;
Ding, Honghua
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
dsDNA
AIM2
exosome
inflammasome
chemotherapy
intestinal toxicity
DW10075, a novel selective and small-molecule inhibitor of VEGFR, exhibits antitumor activities both in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 3, 页码: 398-407
作者:
Li, Meng-yuan
;
Lv, Yong-cong
;
Tong, Lin-jiang
;
Peng, Ting
;
Qu, Rong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
DW10075
VEGF/VEGF receptor inhibitor
antitumor
angiogenesis
U87-MG human glioblastoma
Molecularly targeted cancer therapy: some lessons from the past decade
期刊论文
TRENDS IN PHARMACOLOGICAL SCIENCES, 2014, 卷号: 35, 期号: 1, 页码: 41-50
作者:
Huang, Min
;
Shen, Aijun
;
Ding, Jian
;
Geng, Meiyu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
tumor heterogeneity
resistance
personalized medicine
biomarker
co-clinical trial
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