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科研机构
上海药物研究所 [79]
内容类型
期刊论文 [78]
会议论文 [1]
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2021 [2]
2020 [5]
2019 [2]
2018 [4]
2017 [6]
2016 [6]
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Pharmacolo... [6]
Chemistry [5]
Biochemist... [2]
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共79条,第1-10条
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The double faced role of xanthine oxidoreductase in cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Chen, Man-Man
;
Meng, Ling-Hua
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/01/04
xanthine oxidoreductase (XOR)
ROS
uric acid
cancer therapy
Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199
作者:
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Liang, Xiaoying
;
Lan, Yuan
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/04
The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling
期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10
作者:
Xie, Zhifu
;
Jiang, Haowen
;
Liu, Wei
;
Zhang, Xinwen
;
Chen, Dakai
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/21
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Shui-mei
;
Xie, Zhi-fu
;
Zhang, Yang-ming
;
Zhang, Xin-wen
;
Zhou, Chen-dong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
adenosine 5 '-monophosphate-activated protein kinase
AMPK activator
C24
liver
triglycerides
cholesterol
VLDL
hypolipidemic drug
metabolic syndrome
Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Yu, Yan-yan
;
Cui, Shi-chao
;
Zheng, Tian-nan
;
Ma, Hai-jian
;
Xie, Zhi-fu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
insulin resistance
sarsasapogenin
adipose tissue inflammation
macrophage-adipocyte crosstalk
IKK/NF-kappa B
JNK
Establishment of a mouse model of cancer cachexia with spleen deficiency syndrome and the effects of atractylenolide I
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 237-248
作者:
Zhang, Wan-li
;
Li, Na
;
Shen, Qiang
;
Fan, Men
;
Guo, Xiao-dong
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/07/01
cancer cachexia
traditional Chinese medicine
spleen deficiency
animal model
muscle atrophy
fat lipolysis
atractylenolide I
metabolic syndrome
establishmentofamousemodelofcancercachexiawithspleendeficiencysyndromeandtheeffectsofatractylenolidei
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 237
作者:
Zhang Wanli
;
Li Na
;
Shen Qiang
;
Fan Men
;
Guo Xiaodong
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2020/07/01
cancer cachexia
traditional Chinese medicine
spleen deficiency
animal model
muscle atrophy
fat lipolysis
atractylenolide I
metabolic syndrome
Pyrrole-Hemoglobin Adducts, a More Feasible Potential Biomarker of Pyrrolizidine Alkaloid Exposure
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 6, 页码: 1027-1039
作者:
Ma, Jiang
;
Ruan, Jianqing
;
Chen, Xinmeng
;
Li, Dongping
;
Yao, Sheng
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Biomimetic synthesis of the natural product salviadione and its hybrids: discovery of tissue-specific anti-inflammatory agents for acute lung injury
期刊论文
CHEMICAL SCIENCE, 2019, 卷号: 10, 期号: 17, 页码: 4667-4672
作者:
Ding, Chunyong
;
Chen, Hongjin
;
Liang, Bin
;
Jiao, Mingkun
;
Liang, Guang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 11, 页码: 3403-3414
作者:
Lu, Yao
;
Ma, Jiang
;
Song, Zijing
;
Ye, Yang
;
Fu, Peter P.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid
Retrorsine
ATP5B
Mitochondrial damage
Pyrrole-protein adduct
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