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科研机构
上海药物研究所 [145]
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期刊论文 [138]
项目 [4]
会议论文 [2]
学位论文 [1]
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2021 [3]
2020 [12]
2019 [8]
2018 [4]
2017 [14]
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Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 51, 页码: 5
作者:
Wang, Leiming
;
Li, Xin
;
Cui, Hong
;
Lei, Xinsheng
;
Liu, Hongchun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/01
Marine nature products
Plocabulin
PM060184
Synthesis
Antiproliferation
Polyoxygenated cembranoids from the Hainan soft coral Lobophytum crassum
期刊论文
TETRAHEDRON, 2021, 卷号: 90, 页码: 7
作者:
Yin, Fang-Zhou
;
Yao, Li-Gong
;
Zhang, Zai-Yong
;
Wang, Jian-Rong
;
Wang, Hong
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/08/17
Soft coral
Marine natural products
Cembranoids
Stereochemistry
Recent Progress in Marine Mollusks from The South China Sea: Chemical and Ecological Studies
期刊论文
MINI-REVIEWS IN ORGANIC CHEMISTRY, 2021, 卷号: 18, 期号: 3, 页码: 270-281
作者:
Li, Song-Wei
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/05/24
Bioactivity
gastropoda
marine-derived drugs
mollusks
secondary metabolites
The South China Sea
Chemical ecology-driven discovery of bioactive marine natural products as potential drug leads
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2020, 卷号: 18, 期号: 11, 页码: 837-838
作者:
Li Xu-Wen
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  |  
浏览/下载:2/0
  |  
提交时间:2021/05/24
Rare new bicyclic cembranoid ethers and a novel trihydroxy prenylated guaiane from the Xisha soft coral Lobophytum sp
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 103, 页码: 12
作者:
Li, Song-Wei
;
Cuadrado, Cristina
;
Huan, Xia-Juan
;
Yao, Li-Gong
;
Miao, Ze-Hong
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/12/21
Soft coral
Lobophytum
Cembranoids
Marine natural products
Quantum mechanical calculations
Diving into the world of marine 2,11-cyclized cembranoids: a summary of new compounds and their biological activities
期刊论文
NATURAL PRODUCT REPORTS, 2020, 卷号: 37, 期号: 10, 页码: 1367-1383
作者:
Li, Geng
;
Dickschat, Jeroen S.
;
Guo, Yue-Wei
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  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
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  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Program of Open Studio for Druggability Research of Marine Natural Products, Pilot National Laboratory for Marine Science and Technology (Qingdao, China)
项目
资助机构: Program of Open Studio for Druggability Research of Marine Natural Products, Pilot National Laboratory for Marine Science and Technology (Qingdao, China), 2020-
-
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  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Hepatoprotective effects of total phenylethanoid glycosides from Acanthus ilicifolius L. against carbon tetrachloride-induced hepatotoxicity
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 256, 页码: 8
作者:
Zhang, Meng-Qi
;
Ren, Xia
;
Zhao, Qing
;
Yue, Shi-Jun
;
Fu, Xiu-Mei
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Acanthus ilicifolius L.
Total phenylethanoid glycosides
Hepatoprotective
Antioxidant
Complex Polypropionates from a South China Sea Photosynthetic Mollusk: Isolation and Biomimetic Synthesis Highlighting Novel Rearrangements
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 9
作者:
Wu, Qihao
;
Li, Song-Wei
;
Xu, Heng
;
Wang, Hong
;
Hu, Pei
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
biomimetic synthesis
biosynthetic rearrangements
marine natural products
polyketides
Sacoglossan mollusk
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