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Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity 期刊论文
ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22
作者:  Hu, Lin;  Chen, Fuxian;  Wu, Chao;  Wang, Jun;  Chen, Si-si
收藏  |  浏览/下载:38/0  |  提交时间:2022/01/18
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation 期刊论文
IMMUNITY, 2021, 卷号: 54, 期号: 4, 页码: 632-+
作者:  Wang, Yan;  Fu, Zunyun;  Li, Xutong;  Liang, Yinming;  Pei, Siyu
收藏  |  浏览/下载:61/0  |  提交时间:2021/06/11
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168 期刊论文
NATURE CELL BIOLOGY, 2018, 卷号: 20, 期号: 3, 页码: 320-+
作者:  Xie, Xiaoduo;  Hu, Hongli;  Tong, Xinyuan;  Li, Long;  Liu, Xiangyuan
收藏  |  浏览/下载:100/0  |  提交时间:2019/01/08
Aspirin disrupts the mTOR-Raptor complex and potentiates the anti-cancer activities of sorafenib via mTORC1 inhibition 期刊论文
CANCER LETTERS, 2017, 卷号: 406, 页码: 105-115
作者:  Sun, Danni;  Liu, Hongchun;  Dai, Xiaoyang;  Zheng, Xingling;  Yan, Juan
收藏  |  浏览/下载:47/0  |  提交时间:2019/01/08
pH-Sensitive Nano-Complexes Overcome Drug Resistance and Inhibit Metastasis of Breast Cancer by Silencing Akt Expression 期刊论文
THERANOSTICS, 2017, 卷号: 7, 期号: 17, 页码: 4204-4216
作者:  Yin, Jieying;  Lang, Tianqun;  Cun, Dongmei;  Zheng, Zhong;  Huang, Yan
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 67071-67086
作者:  Qian, Jianchang;  Chen, Yaqing;  Meng, Tao;  Ma, Lanping;  Meng, Lanfang
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
HC toxin (a HDAC inhibitor) enhances IRS1-Akt signalling and metabolism in mouse myotubes 期刊论文
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2015, 卷号: 55, 期号: 3, 页码: 197-207
作者:  Tan, Hayden Weng Siong;  Sim, Arthur Yi Loong;  Huang, Su Ling;  Leng, Ying;  Long, Yun Chau
收藏  |  浏览/下载:25/0  |  提交时间:2019/01/08
Discovery of the Novel mTOR Inhibitor and Its Antitumor Activities In Vitro and In Vivo 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2013, 卷号: 12, 期号: 6, 页码: 950-958
作者:  Xie, Hua;  Lee, Mee-Hyun;  Zhu, Feng;  Reddy, Kanamata;  Huang, Zunnan
收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08
Arctigenin alleviates ER stress via activating AMPK 期刊论文
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 7, 页码: 941-952
作者:  Gu, Yuan;  Sun, Xiao-xiao;  Ye, Ji-ming;  He, Li;  Yan, Shou-sheng
收藏  |  浏览/下载:19/0  |  提交时间:2019/01/08
S9, a Novel Anticancer Agent, Exerts Its Anti-Proliferative Activity by Interfering with Both PI3K-Akt-mTOR Signaling and Microtubule Cytoskeleton 期刊论文
PLOS ONE, 2009, 卷号: 4, 期号: 3
作者:  Zhang, Chao;  Yang, Na;  Yang, Chun-hao;  Ding, Hua-sheng;  Luo, Cheng
收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08


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