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CORC

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Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:  Zhang, Ning;  Tian, Yu-Nan;  Zhou, Li-Na;  Li, Meng-Zhu;  Chen, Hua-Dong
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645
作者:  Wang, Lei;  Zhu, Xi;  Li, Lili;  Li, Lin;  Fu, Li
收藏  |  浏览/下载：75/0  |  提交时间：2021/06/11
Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文
Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1
作者:  Ning Zhang;  Yu-Nan Tian;  Li-Na Zhou;  Meng-Zhu Li;  Hua-Dong Chen
收藏  |  浏览/下载：18/0  |  提交时间：2021/12/01
Pharmacologic characterization of fluzoparib, a novel poly(ADP-ribose) polymerase inhibitor undergoing clinical trials 期刊论文
CANCER SCIENCE, 2019, 卷号: 110, 期号: 3, 页码: 1064-1075
作者:  Wang, Lei;  Yang, Changyong;  Xie, Chengying;  Jiang, Jiahua;  Gao, Mingzhao
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:  Tian, Qian-Ting;  Ding, Chun-Yong;  Song, Shan-Shan;  Wang, Ying-Qing;  Zhang, Ao
收藏  |  浏览/下载：40/0  |  提交时间：2019/01/08
Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining 期刊论文
CANCER COMMUNICATIONS, 2018, 卷号: 38
作者:  Zhang, Minjie;  Wang, Liu;  An, Ke;  Cai, Jun;  Li, Guochao
收藏  |  浏览/下载：60/0  |  提交时间：2019/01/08
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168 期刊论文
NATURE CELL BIOLOGY, 2018, 卷号: 20, 期号: 3, 页码: 320-+
作者:  Xie, Xiaoduo;  Hu, Hongli;  Tong, Xinyuan;  Li, Long;  Liu, Xiangyuan
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
Hypoxia induces universal but differential drug resistance and impairs anticancer mechanisms of 5-fluorouracil in hepatoma cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1642-1654
作者:  Li, Jing-qiu;  Wu, Xian;  Gan, Lu;  Yang, Xiang-liang;  Miao, Ze-hong
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531
作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells 期刊论文
JOURNAL OF CELL BIOLOGY, 2017, 卷号: 216, 期号: 2, 页码: 409-424
作者:  Qu, Jia;  Sun, Wenyi;  Zhong, Jie;  Lv, Hao;  Zhu, Mingrui
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08

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