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科研机构
上海药物研究所 [83]
内容类型
期刊论文 [83]
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2021 [7]
2020 [6]
2019 [11]
2018 [7]
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2016 [8]
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Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-)Rag2(-/-)IL2rg(-/-) Rats
期刊论文
ADVANCED SCIENCE, 2021, 页码: 14
作者:
Zhang, Ludi
;
Ge, Jian-Yun
;
Zheng, Yun-Wen
;
Sun, Zhen
;
Wang, Chenhua
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
bioreactor
humanized liver
liver xeno-repopulation
pharmacological study
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-κB pathway
期刊论文
Cancer Cell International, 2021, 卷号: 21, 期号: 1
作者:
Gao,Xuejie
;
Li,Bo
;
Ye,Anqi
;
Wang,Houcai
;
Xie,Yongsheng
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2021/06/11
Multiple myeloma
Anti-tumor activity
NF-κB
A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-kappa B pathway
期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 10
作者:
Gao, Xuejie
;
Li, Bo
;
Ye, Anqi
;
Wang, Houcai
;
Xie, Yongsheng
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Multiple myeloma
Anti-tumor activity
NF-kappa B
GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 2, 页码: 941-957
作者:
Wang, Congcong
;
Zhang, Yu-Fang
;
Guo, Shimeng
;
Zhao, Quan
;
Zeng, Yanping
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells
期刊论文
ONCOIMMUNOLOGY, 2021, 卷号: 10, 期号: 1, 页码: 13
作者:
Fan, Dandan
;
Yue, Qi
;
Chen, Jian
;
Wang, Cong
;
Yu, Ruilin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Wnt/beta-catenin
IDH1-wildtype glioblastoma
Microglia
Phenotypic polarization
A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2021, 卷号: 13, 期号: 10, 页码: 11439-11449
作者:
Bu, Wenxuan
;
Li, Bo
;
Feng, Lijin
;
Feng, Qilin
;
Hu, Ke
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/16
Multiple myeloma
DCZ0858
mTOR
bone marrow microenvironment
cell proliferation
cell apoptosis
Ternary Regulation of Tumor Microenvironment by Heparanase-Sensitive Micelle-Loaded Monocytes Improves Chemo-Immunotherapy of Metastatic Breast Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 12
作者:
Lang, Tianqun
;
Zheng, Zhong
;
Huang, Xin
;
Liu, Yiran
;
Zhai, Yihui
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/05/24
breast cancer
chemo-immunotherapy
heparinase
monocytes
tumor environments
BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis
期刊论文
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Li, Guang
;
Zheng, Yan-Hua
;
Xu, Li
;
Feng, Juan
;
Tang, Hai-Long
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/12/24
apoptosis
BRD4 inhibitor
G1 phase cell cycle checkpoint
multiple myeloma
Self-assembling and self-formulating prodrug hydrogelator extends survival in a glioblastoma resection and recurrence model
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2020, 卷号: 319, 页码: 311-321
作者:
Schiapparelli, Paula
;
Zhang, Pengcheng
;
Lara-Velazquez, Montserrat
;
Guerrero-Cazares, Hugo
;
Lin, Ran
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Prodrug
Hydrogel
Glioblastoma
Local therapy
Chemotherapy
Camptothecin
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