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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 The mTOR inhibitor AZD8055 overcomes tamoxifen resistance in breast cancer cells by down-regulating HSPB8 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1338-1346 作者:  Shi, Jia-jie;  Chen, Si-meng;  Guo, Chen-Liang;  Li, Yi-xue;  Ding, Jian 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 tamoxifen resistance  HSPB8  AZD8055  estrogen receptor  mTOR inhibitor   Discovery of FS36 as a Novel Human Hsp90 Inhibitor 期刊论文 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 45, 期号: 7, 页码: 736-744 作者:  Li Gen;  Lu Kai-Kai;  Li Jian;  Yin Xiu-Shan;  Zhao Dong 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 heat shock protein 90  antitumor drugs  inhibitor  X-ray diffraction  complex crystal structure   Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 12, 页码: 1587-1596 作者:  Wang, Yue-qin;  Shen, Ai-jun;  Sun, Jing-ya;  Wang, Xin;  Liu, Hong-chun 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 non-small cell lung cancer  gefitinib resistance  Hsp90   Regulation of Ubiquitin-like with Plant Homeodomain and RING Finger Domain 1 (UHRF1) Protein Stability by Heat Shock Protein 90 Chaperone Machinery 期刊论文 JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 38, 页码: 20125-20135 作者:  Ding, Guangjin;  Chen, Peilin;  Zhang, Hui;  Huang, Xiaojie;  Zang, Yi 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 70-kilodalton heat shock protein (HSP70)  cancer therapy  DNA methylation  protein degradation  ubiquitin   Y-632 inhibits heat shock protein 90 (Hsp90) function by disrupting the interaction between Hsp90 and Hsp70/Hsp90 organizing protein, and exerts antitumor activity in vitro and in vivo 期刊论文 CANCER SCIENCE, 2016, 卷号: 107, 期号: 6, 页码: 782-790 作者:  Wang, Wenqian;  Liu, Yang;  Zhao, Zhixin;  Xie, Chengying;  Xu, Yongping 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 Hop  Hsp90  imatinib resistance  thiol oxidation  Y-632   targetinghsp90withfs108circumventsgefitinlbresistanceinegfrmutantnonsmallcelllungcancercells 期刊论文 actapharmacologicasinica, 2016, 卷号: 37, 期号: 12, 页码: 1587 作者:  Wang Yueqin;  Shen Aijun;  Sun Jingya;  Wang Xin;  Liu Hongchun 收藏  |  浏览/下载：1/0  |  提交时间：2020/07/01 non-small cell lung cancer  gefitinlb resistance  Hsp90   Targeting Hsp90 with FS-108 circumvents gefitinlb resistance in EGFR mutant non-small cell lung cancer cells 期刊论文 Acta Pharmacologica Sinica, 2016, 卷号: 37, 期号: 12, 页码: 1587 作者:  Wang Yueqin;  Shen Aijun;  Sun Jingya;  Wang Xin;  Liu Hongchun 收藏  |  浏览/下载：13/0  |  提交时间：2020/12/24 non-small cell lung cancer  gefitinlb resistance  Hsp90   FS23 binds to the N-terminal domain of human Hsp90: A novel small inhibitor for Hsp90 期刊论文 NUCLEAR SCIENCE AND TECHNIQUES, 2015, 卷号: 26, 期号: 6 作者:  Li Jian;  Shi Feng;  Chen Dan-Qi;  Cao Hui-Ling;  Xiong Bing 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Heat shock protein 90  N-terminal domain  Inhibitor  X-ray diffraction  Interactions   Identification of matrine as a promising novel drug for hepatic steatosis and glucose intolerance with HSP72 as an upstream target 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2015, 卷号: 172, 期号: 17, 页码: 4303-4318 作者:  Zeng, Xiao-Yi;  Wang, Hao;  Bai, Fang;  Zhou, Xiu;  Li, Song-Pei 收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08 Identification of epipolythiodioxopiperazines HDN-1 and chaetocin as novel inhibitor of heat shock protein 90 期刊论文 ONCOTARGET, 2015, 卷号: 6, 期号: 7, 页码: 5263-5274 作者:  Song, Xiaoping;  Zhao, Zhimin;  Qi, Xin;  Tang, Shuai;  Wang, Qiang 收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08 pipolythiodioxopiperazines  HDN-1  chaetocin  inhibitor  Hsp90