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科研机构
上海药物研究所 [29]
内容类型
期刊论文 [29]
发表日期
2021 [2]
2020 [2]
2018 [3]
2016 [4]
2015 [2]
2014 [3]
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Chemistry [1]
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The potent radioprotective agents: Novel nitronyl nitroxide radical spin-labeled resveratrol derivatives
期刊论文
FITOTERAPIA, 2021, 卷号: 155, 页码: 7
作者:
Luo, Guoying
;
Sun, Lanlan
;
Li, Heng
;
Chen, Jia
;
He, Peilan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/12/01
Ionizing radiation
Resveratrol
Nitronyl nitroxide radical
Radioprotection effects
Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism
期刊论文
NATURE METABOLISM, 2021, 页码: 31
作者:
Xu, Yanyong
;
Li, Yuanyuan
;
Jadhav, Kavita
;
Pan, Xiaoli
;
Zhu, Yingdong
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/05/24
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Selective and sensitive fluorescence imaging reveals microenvironment-dependent behavior of NO modulators in the endothelial system
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 5, 页码: 466-472
作者:
Dong, Ying
;
Li, Xiao-Rong
;
Li, Jia
;
Zang, Yi
;
Li, Xin
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2020/12/21
Nitric oxide modulator
Drug screen
Fluorescence imaging
Microenvironment
Endothelial cell
The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine
期刊论文
MOLECULAR GENETICS AND METABOLISM REPORTS, 2018, 卷号: 17, 页码: 46-52
作者:
Li, Hong
;
Zhao, Lihua
;
Singh, Rani
;
Ham, J. Nina
;
Fadoju, Doris O.
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2019/01/08
Glucagon receptor
Newborn screening
GCGR mutation
Hyperaminoacidemia
Mahvash disease
Pancreatic alpha cell hyperplasia (ACH)
Pancreatic neuroendocrine tumor (PNET)
Effect of Medium-chain Fatty Acid-sensing Receptor GPR84 on Glucose and Lipid Metabolism in Mice
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 45, 期号: 8, 页码: 853-864
作者:
Fang You-Chen
;
Zheng Yang
;
Zheng Qing
;
Li Jing
;
Xie Xin
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
GPR84
medium-chain fatty acid-sensing receptor
obesity
lipid metabolism
hypercholesterolemia
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Li, Xun
;
Qiu, Zidong
;
Jin, Qinghao
;
Chen, Guilin
;
Guo, Mingquan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
colon cancer
Toddalia asiatica Lam.
G2/M arrest
apoptosis
reactive oxygen species
Altered intestinal microbiota-host mitochondria crosstalk in new onset Crohn's disease
期刊论文
NATURE COMMUNICATIONS, 2016, 卷号: 7
作者:
Mottawea, Walid
;
Chiang, Cheng-Kang
;
Muelbauer, Marcus
;
Starr, Amanda E.
;
Butcher, James
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Novel CHOP activator LGH00168 induces necroptosis in A549 human lung cancer cells via ROS-mediated ER stress and NF-kappa B inhibition
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1381-1390
作者:
Ma, Yi-ming
;
Peng, Yan-min
;
Zhu, Qiong-hua
;
Gao, An-hui
;
Chao, Bo
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
CHOP
LGH00168
ER stress
NF-kappa B
necroptosis
RIP1
ROS
non-small cell lung cancer A549 cells
cancer xenograft mice
novelchopactivatorlgh00168inducesnecroptosisina549humanlungcancercellsviarosmediatederstressandnfkbinhibition
期刊论文
actapharmacologicasinica, 2016, 卷号: 37, 期号: 10, 页码: 1381
作者:
Ma Yiming
;
Peng Yanmin
;
Zhu Qionghua
;
Gao Anhui
;
Chao Bo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
CHOP
LGH00168
ER stress
NF-kB
necroptosis
RIP1
ROS
non-small cell lung cancer A549 cells
cancer xenograft mice
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