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科研机构
上海药物研究所 [29]
内容类型
期刊论文 [29]
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2021 [2]
2020 [4]
2018 [2]
2017 [2]
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Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
Elksnis, Andris
;
Schiffer, Tomas A.
;
Palm, Fredrik
;
Wang, Yun
;
Cen, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387
作者:
Li, Zhe
;
Li, Xin
;
Huang, Yi-You
;
Wu, Yaoxing
;
Liu, Runduo
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2020/12/24
virtual screening
SARS-CoV-2
drug repurposing
free energy perturbation
main protease
Overview of therapeutic drug research for COVID-19 in China
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Li, Heng
;
Yang, Li
;
Liu, Fei-fei
;
Ma, Xin-na
;
He, Pei-lan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/24
SARS-CoV-2
COVID-19
novel coronavirus pneumonia
therapeutic drugs
anti-SARS-CoV-2 agents
favipiravir
hydroxychloroquine
traditional Chinese medicine
Short-term exposure to ZnO/MCB persistent free radical particles causes mouse lung lesions via inflammatory reactions and apoptosis pathways
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 261, 页码: 8
作者:
Zhang, Xing
;
Gu, Wenyi
;
Ma, Zhongliang
;
Liu, Yun
;
Ru, Hongbo
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
Environmentally persistent free radicals
Lung cells and tissues
Oxidative stress
Inflammatory
Apoptosis
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network -molecular docking-LC-MSE analysis
期刊论文
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2020, 卷号: 18, 期号: 3, 页码: 229-241
作者:
Zhang, Zi-jia
;
Wu, Wen-yong
;
Hou, Jin-jun
;
Zhang, Lin-lin
;
Li, Fei-fei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Lung-toxin Dispelling Formula No. 1
COVID-19
3C-like protease
Network pharmacology
Molecular docking
Meridian tropism
Material basis studies of anti-Influenza A active ingredients in Tanreqing Injection
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2018, 卷号: 32, 期号: 2
作者:
Zhu, Haiyan
;
Chen, Mingcang
;
Shi, Xunlong
;
Shi, Chenchen
;
Huang, Chenggang
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
antiviral research
component analysis
Influenza A virus
LC/QTOF/MS
Tanreqing Injection
Shufeng Jiedu Capsules Alleviate Lipopolysaccharide-Induced Acute Lung Inflammatory Injury via Activation of GPR18 by Verbenalin
期刊论文
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, 卷号: 50, 期号: 2, 页码: 629-639
作者:
Yuan, Ying
;
Liao, Qingwu
;
Xue, Mingming
;
Shi, Yujing
;
Rong, Ling
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Dissociative role for dorsal hippocampus in mediating heroin self-administration and relapse through CDK5 and RhoB signaling revealed by proteomic analysis
期刊论文
ADDICTION BIOLOGY, 2017, 卷号: 22, 期号: 6, 页码: 1731-1742
作者:
Chen, Zhong-Guo
;
Liu, Xing
;
Wang, Weisheng
;
Geng, Fan
;
Gao, Jing
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
CDK5
dorsal hippocampus
heroin self-administration
label-free proteomic analysis
RhoB
the centrifugal proteomic reactor
Comparative Evaluation of Small Molecular Additives and Their Effects on Peptide/Protein Identification
期刊论文
ANALYTICAL CHEMISTRY, 2017, 卷号: 89, 期号: 11, 页码: 5785-5793
作者:
Gao, Jing
;
Zhong, Shaoyun
;
Zhou, Yanting
;
He, Han
;
Peng, Shuying
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
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