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科研机构
上海药物研究所 [27]
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期刊论文 [27]
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2021 [2]
2020 [3]
2019 [2]
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Concise synthesis of N-phosphorylated amides through three-component reactions
期刊论文
GREEN CHEMISTRY, 2021, 页码: 5
作者:
Zhu, Yuan-Yuan
;
Zhang, Tao
;
Zhou, Linlin
;
Yang, Shang-Dong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/12/16
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:
He, Qian
;
Wei, Yuanyuan
;
Liu, Xiao
;
Ye, Rongrong
;
Kong, Linghui
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2021/11/04
Diterpene Biosynthesis in Catenulispora acidiphila: On the Mechanism of Catenul-14-en-6-ol Synthase
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 6
作者:
Li, Geng
;
Guo, Yue-Wei
;
Dickschat, Jeroen S.
收藏
  |  
浏览/下载:113/0
  |  
提交时间:2021/05/24
biosynthesis
enzyme mechanisms
isotopes
substrate analogues
terpenoids
Manipulating the Click Reactivity of Dibenzoazacyclooctynes: From Azide Click Component to Caged Acylation Reagent by Silver Catalysis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 6
作者:
Shi, Wei
;
Tang, Feng
;
Ao, Jiwei
;
Yu, Qun
;
Liu, Junjie
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/21
acylation
click chemistry
peptides
rearrangements
silver
Complex Polypropionates from a South China Sea Photosynthetic Mollusk: Isolation and Biomimetic Synthesis Highlighting Novel Rearrangements
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 9
作者:
Wu, Qihao
;
Li, Song-Wei
;
Xu, Heng
;
Wang, Hong
;
Hu, Pei
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
biomimetic synthesis
biosynthetic rearrangements
marine natural products
polyketides
Sacoglossan mollusk
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2020/07/01
Proteomic analysis of male rat nucleus accumbens, dorsal hippocampus and amygdala on conditioned place aversion induced by morphine withdrawal
期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2019, 卷号: 372, 页码: 8
作者:
Guo, Liu-bin
;
Yu, Chuan
;
Ling, Qing-lan
;
Fu, Yu
;
Wang, Yu-jun
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Morphine withdrawal
Aversive memories
Proteomics
Synaptic plasticity
Amygdala
Dorsal hippocampus
Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors
期刊论文
Cell reports, 2018, 卷号: 25, 期号: 13, 页码: 3582-3590.e4
作者:
Zhang, Jin-Bao
;
Chang, Shenghai
;
Xu, Pan
;
Miao, Miao
;
Wu, Hangjun
收藏
  |  
浏览/下载:116/0
  |  
提交时间:2019/01/08
The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent kappa-Opioid Agonistic Activities
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 766-776
作者:
Li, Wei
;
Long, Jian-Dong
;
Qian, Yuan-Yuan
;
Long, Yu
;
Xu, Xue-Jun
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
kappa-opioid receptor
mu-opioid receptor
nepenthones
4,5-epoxymorphinans
pharmacological heterogeneity
structure activity relationship
binding structure
Drainage dynamics of thin liquid foam films containing soft PNiPAM microgels: influence of the cross-linking density and concentration
期刊论文
Soft matter, 2016, 卷号: 13, 期号: 1, 页码: 170-180
作者:
Keal, L
;
Lapeyre, V
;
Ravaine, V
;
Schmitt, V
;
Monteux, C
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
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