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Optimization of piperidine constructed peptidyl derivatives as proteasome inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 14
作者:  Zhao, Yanmei;  Xu, Lei;  Zhang, Jiankang;  Zhang, Mengmeng;  Lu, Jingyi
收藏  |  浏览/下载:23/0  |  提交时间:2021/05/24
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:  Chen, Xiang-ling;  Liu, Peng;  Zhu, Wei-liang;  Lou, Li-guang
收藏  |  浏览/下载:50/0  |  提交时间:2020/07/01
Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14
作者:  Zhang, Xin;  Xu, Fang;  Tong, Linjiang;  Zhang, Tao;  Xie, Hua
收藏  |  浏览/下载:81/0  |  提交时间:2020/07/01
Deubiquitinase ubiquitin-specific protease 9X regulates the stability and function of E3 ubiquitin ligase ring finger protein 115 in breast cancer cells 期刊论文
CANCER SCIENCE, 2019, 卷号: 110, 期号: 4, 页码: 1268-1278
作者:  Lu, Qin;  Lu, Dayun;  Shao, Zhi-Ming;  Li, Da-Qiang
收藏  |  浏览/下载:58/0  |  提交时间:2020/07/01
Design, synthesis, and biological evaluation of novel phenol ether derivatives as non-covalent proteasome inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 161, 页码: 543-558
作者:  Yu, Jianjun;  Xu, Lei;  Hong, Duidui;  Zhang, Xiaotuan;  Liu, Jieyu
收藏  |  浏览/下载:71/0  |  提交时间:2019/01/08
Inhibition of HSP90 beta Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 20, 页码: 5769-5783
作者:  Zheng, Zu-Guo;  Zhang, Xin;  Liu, Xiao-Xiao;  Jin, Xiu-Xiu;  Dai, Lunzhi
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01
Dihydrocelastrol exerts potent antitumor activity in mantle cell lymphoma cells via dual inhibition of mTORC1 and mTORC2 期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 53, 期号: 2, 页码: 823-834
作者:  Xie, Yongsheng;  Li, Bo;  Bu, Wenxuan;  Gao, Lu;  Zhang, Yong
收藏  |  浏览/下载:98/0  |  提交时间:2019/01/08
SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes 期刊论文
FEBS JOURNAL, 2017, 卷号: 284, 期号: 21, 页码: 3619-3636
作者:  Mo, Yan;  Lin, Ran;  Liu, Peng;  Tan, Minjia;  Xiong, Yue
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Dihydrocelastrol inhibits multiple myeloma cell proliferation and promotes apoptosis through ERK1/2 and IL-6/STAT3 pathways in vitro and in vivo 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2017, 卷号: 49, 期号: 5, 页码: 420-427
作者:  Hu, Liangning;  Wu, Huiqun;  Li, Bo;  Song, Dongliang;  Yang, Guang
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog 期刊论文
NATURE COMMUNICATIONS, 2016, 卷号: 7
作者:  Jin, Jiali;  Liu, Jian;  Chen, Cong;  Liu, Zhenping;  Jiang, Cong
收藏  |  浏览/下载:95/0  |  提交时间:2019/01/08


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