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CORC

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Conformational polymorphs of isotretinoin and their impact on physicochemical and biological properties 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 610, 页码: 10
作者:  Cheng, Yinxiang;  Rong, Xiaoyi;  Xia, Mengyuan;  Zhang, Zaiyong;  Wang, Jian-Rong
收藏  |  浏览/下载：73/0  |  提交时间：2022/01/04
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:  Zhou, Jun;  Zhan, Yan;  Zhong, Dafang;  Chen, Xiaoyan;  Zhang, Yifan
收藏  |  浏览/下载：72/0  |  提交时间：2021/11/04
Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers 期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:  Chen, Zhen-dong;  Chen, Qian;  Zhu, Yun-ting;  Zhang, Yi-fan;  Zhan, Yan
收藏  |  浏览/下载：38/0  |  提交时间：2022/01/04
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity 期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:  Sun, Dongxue;  Gao, Xiaoxia;  Wang, Qiao;  Krausz, Kristopher W.;  Fang, Zhongze
收藏  |  浏览/下载：48/0  |  提交时间：2021/11/04
Interfacial interactions and structures of protic ionic liquids on a graphite surface: A first-principles study and comparison with aprotic ionic liquids 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 11
作者:  Lu, Yunxiang;  Xu, Yanmin;  Lu, Ling;  Xu, Zhijian;  Liu, Honglai
收藏  |  浏览/下载：16/0  |  提交时间：2021/11/04
The inhibitory effect of 225 frequently-used traditional Chinese medicines for CYP3A4 metabolic enzyme by isoform-specific probe 期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 5
作者:  Wei, Wenlong;  Li, Zhenwei;  Li, Hao-jv;  An, Yaling;  Qu, Hua
收藏  |  浏览/下载：33/0  |  提交时间：2021/08/17
TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia 期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 378, 期号: 1, 页码: 20-30
作者:  Wang, Yu;  He, Yang;  Yang, Feipu;  Abame, Melkamu Alemu;  Wu, Chunhui
收藏  |  浏览/下载：37/0  |  提交时间：2021/11/04
Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7
作者:  Pan, Lu-lu;  Chen, Tao;  Hui, Min;  Wang, Shuo;  Fu, Li
收藏  |  浏览/下载：131/0  |  提交时间：2021/05/24

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