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CORC

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Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:  Hu, Ke;  Li, Bo;  Ma, Ruye;  Yi, Hongfei;  Xu, Zhijian
收藏  |  浏览/下载：68/0  |  提交时间：2021/06/11
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming
收藏  |  浏览/下载：36/0  |  提交时间：2021/05/24
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun
收藏  |  浏览/下载：33/0  |  提交时间：2021/05/24
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:  Xi, Mengyu;  He, Wan;  Li, Bo;  Zhou, Jinfeng;  Xu, Zhijian
收藏  |  浏览/下载：44/0  |  提交时间：2020/12/24
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:  Xi, Mengyu;  He, Wan;  Li, Bo;  Zhou, Jinfeng;  Xu, Zhijian
收藏  |  浏览/下载：20/0  |  提交时间：2020/12/24
子宫内膜癌靶向药物治疗研究进展 期刊论文
中国新药与临床杂志, 2020, 卷号: 39, 期号: 1, 页码: 1
作者:  曹海敬;  薛嫚;  李芳;  俸灵林;  丁宏
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:  Fan, Lei;  Qiu, Xiao-xia;  Zhu, Zhi-yuan;  Lv, Jian-lu;  Lu, Jian
收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic PIK3CA(H1047R) accompanied with pro-tumorigenic secretome 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 3, 页码: 817-829
作者:  Liu, Xue-Ling;  Liu, Jia-Li;  Xu, Yi-Chao;  Zhang, Xi;  Wang, Yu-Xiang
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as Potential Simplified Phosphatidylinositol 3-Kinase alpha (PI3Kα) inhibitors 期刊论文
Chemical biology & drug design, 2018
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Song, Kun;  Ruan, Cong
收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08

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