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科研机构
上海药物研究所 [9]
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期刊论文 [8]
学位论文 [1]
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2019 [1]
2014 [1]
2011 [1]
2006 [2]
2005 [3]
2003 [1]
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Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 22, 页码: 6
作者:
Wang, Zhenkang
;
Ma, Chunhua
;
Wang, Yujie
;
Xiao, Qiang
;
Xu, Chenghui
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Gentisides
Neurotrophic activity
Isosteric replacement
Conformational restriction
PC 12 cells
GLCE regulates PC12 cell neuritogenesis induced by nerve growth factor through activating SMAD/ID3 signalling
期刊论文
BIOCHEMICAL JOURNAL, 2014, 卷号: 459, 页码: 405-415
作者:
Li, Jie
;
Fang, Jianping
;
Qin, Yi
;
Liao, Wenfeng
;
Liu, Hailing
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
differentiation
glucuronic acid epimerase (GLCE)
heparan sulfate
inhibitor of DNA binding/differentiation 3 (ID3)
neuritogenesis
Heparanase enhances nerve-growth-factor-induced PC12 cell neuritogenesis via the p38 MAPK pathway
期刊论文
BIOCHEMICAL JOURNAL, 2011, 卷号: 440, 页码: 273-282
作者:
Cui, Hengxiang
;
Shao, Chenghao
;
Liu, Qin
;
Yu, Wenjie
;
Fang, Jianping
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
heparanase
neurite outgrowth
neuritogenesis
neuron differentiation
p38 mitogen-activated protein kinase (MAPK)
Neuroprotective effects of huperzine A: new therapeutic targets for neurodegenerative disease
期刊论文
TRENDS IN PHARMACOLOGICAL SCIENCES, 2006, 卷号: 27, 期号: 12, 页码: 619-625
作者:
Zhang, Hai Yan
;
Tang, Xi Can
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Effects of huperzine A on memory deficits and neurotrophic factors production after transient cerebral ischemia and reperfusio'n in mice
期刊论文
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2006, 卷号: 83, 期号: 4, 页码: 603-611
作者:
Wang, Zhi-fei
;
Tang, Li-li
;
Yan, Han
;
Wang, Yu-jun
;
Tang, Xi-can
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Huperzine A
acetylcholinesterase inhibitor
transient cerebral ischemia and reperfusion
learning and memory
nerve growth factor
brain-derived neurotrophic factor
transforming growth factor-beta(1)
mitogen-activated protein kinase/extracellular signal-regulated kinase
Huperzine A protects SHSY5Y neuroblastoma cells against oxidative stress damage via nerve growth factor production
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2005, 卷号: 519, 期号: 1-2, 页码: 9-15
作者:
Tang, LL
;
Wang, R
;
Tang, XC
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
huperzine A
oxidative stress
nerve growth factor
MAP (mitogen-activated protein) kinase
TrkA (tyrosine kinase A) receptor
Effects of huperzine A on secretion of nerve growth factor in cultured rat cortical astrocytes and neurite outgrowth in rat PC12 cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2005, 卷号: 26, 期号: 6, 页码: 673-678
作者:
Tang, LL
;
Wang, R
;
Tang, XC
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/01/08
huperzine A
nerve growth factor
neurite outgrowth
acetylcholinesterase inhibitors
Characterization of a rhamnogalacturonan and a xyloglucan from Nerium indicum and their activities on PC12 pheochromocytoma cells
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2003, 卷号: 66, 期号: 1, 页码: 7-10
作者:
Ding, K
;
Fang, JN
;
Dong, TX
;
Tsim, KWK
;
Wu, HM
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
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