CORC

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CORC

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Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma 期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:  Chen, Zi-qi;  Cao, Zhe-rui;  Wang, Yi;  Zhang, Xi;  Xu, Lan
收藏  |  浏览/下载：53/0  |  提交时间：2021/12/16
CYH33  MYC  P300  BET  B cell lymphoma  PI3K  
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：29/0  |  提交时间：2021/12/16
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Intestinal MYC modulates obesity-related metabolic dysfunction 期刊论文
NATURE METABOLISM, 2021, 页码: 37
作者:  Luo, Yuhong;  Yang, Shoumei;  Wu, Xuan;  Takahashi, Shogo;  Sun, Lulu
收藏  |  浏览/下载：29/0  |  提交时间：2021/08/17
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:  Gao, Dingding;  Jin, Nan;  Fu, Yixian;  Zhu, Yueyue;  Wang, Yujie
收藏  |  浏览/下载：43/0  |  提交时间：2021/06/11
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming
收藏  |  浏览/下载：36/0  |  提交时间：2021/05/24
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei
收藏  |  浏览/下载：51/0  |  提交时间：2021/05/24
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi
收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24
Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer 期刊论文
ADVANCED SCIENCE, 2021, 页码: 12
作者:  Sun, Fang;  Zhu, Qiurong;  Li, Tianliang;  Saeed, Madiha;  Xu, Zhiai
收藏  |  浏览/下载：46/0  |  提交时间：2021/05/24
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24

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