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科研机构
上海药物研究所 [186]
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期刊论文 [181]
会议论文 [5]
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2021 [3]
2020 [4]
2019 [5]
2018 [8]
2017 [6]
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A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Determination of maytansinoids in Trewia nudiflora using QuEChERS extraction combined with HPLC
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7
作者:
Li, Ya-Nan
;
Li, Jia-Nan
;
Ouyang, Qin
;
Zhou, Yu-Bo
;
Lei, Chun
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
Trewia nudiflora
QuEChERS method
Maytansinoids
HPLC
Characterization and quantitative determination of henagliflozin metabolites in humans
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:
Chen, Zhendong
;
Li, Liang
;
Zhan, Yan
;
Zhang, Yifan
;
Liu, Haiyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Henagliflozin
Metabolism
LC-MS/MS
Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8
作者:
Zhang, Mengqi
;
Liu, Haiming
;
He, Jiajin
;
Gui, Yuzhou
;
Qian, Hongjie
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
TPN171
LC-MS/MS
Human plasma
Protein precipitation
Intrinsic stability study of L-alpha-glycerylphosphorylcholine with HPLC method development and validation
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 188, 页码: 6
作者:
Zhao, Hongwei
;
Sun, Ling
;
Chen, Huanhuan
;
Xiang, Lili
;
Chen, Dongying
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/12/24
L-alpha-Glycerylphosphorylcholine
Phosphate ester bond
Forced degradation
HPLC
Intrinsic stability
Kinetics study
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:
Qiu, Yanan
;
Tang, Chongzhuang
;
Li, Ranran
;
Cao, Sumin
;
Zhang, Yuqiang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
LC-MS
MS
N-oxide
stability
sutetinib
Qualitative and quantitative determination of anaprazole and its major metabolites in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 183, 页码: 10
作者:
Tang, Chongzhuang
;
Li, Liang
;
Ma, Xifeng
;
Wang, Jin
;
Chen, Bo
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/07/01
Metabolite identification
LC-MS/MS
UPLC-UV/Q-TOF
Anaprazole
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:
Liu, Xiaoyun
;
Li, Wei
;
Zhang, Yifan
;
Jian, Yong
;
Zhao, Qianyu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
LC-MS/MS
Alflutinib
AST2818
Pharmacokinetics
Human plasma
Simultaneous determination of cinobufagin and its five metabolites in rat plasma by LC-MS/MS for characterization of metabolic profiles and pharmacokinetic study
期刊论文
ANALYTICAL METHODS, 2019, 卷号: 11, 期号: 42, 页码: 5464-5471
作者:
Wei, Wenlong
;
Li, Haojv
;
Li, Zhenwei
;
Qu, Hua
;
Da, Juan
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
Enantioselective determination of ketamine in dog plasma by chiral liquid chromatography-tandem mass spectrometry
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2019, 卷号: 33, 期号: 9, 页码: 8
作者:
Li, Ranran
;
Zhong, Kan
;
Jiang, Jinfang
;
Zhan, Yuan
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
chiral stationary phases
enantioselective LC-MS
MS
ketamine
stereoselective pharmacokinetics
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