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The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168 期刊论文
NATURE CELL BIOLOGY, 2018, 卷号: 20, 期号: 3, 页码: 320-+
作者:  Xie, Xiaoduo;  Hu, Hongli;  Tong, Xinyuan;  Li, Long;  Liu, Xiangyuan
收藏  |  浏览/下载:100/0  |  提交时间:2019/01/08
Cyclic helix B peptide protects HK-2 cells from oxidative stress by inhibiting ER stress and activating Nrf2 signalling and autophagy 期刊论文
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 16, 期号: 6, 页码: 8055-8061
作者:  Li, Long;  Lin, Miao;  Zhang, Lexi;  Huang, Shang;  Hu, Chao
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Aspirin disrupts the mTOR-Raptor complex and potentiates the anti-cancer activities of sorafenib via mTORC1 inhibition 期刊论文
CANCER LETTERS, 2017, 卷号: 406, 页码: 105-115
作者:  Sun, Danni;  Liu, Hongchun;  Dai, Xiaoyang;  Zheng, Xingling;  Yan, Juan
收藏  |  浏览/下载:47/0  |  提交时间:2019/01/08
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 67071-67086
作者:  Qian, Jianchang;  Chen, Yaqing;  Meng, Tao;  Ma, Lanping;  Meng, Lanfang
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
HSP90 inhibitor AUY922 abrogates up-regulation of RTKs by mTOR inhibitor AZD8055 and potentiates its antiproliferative activity in human breast cancer 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2014, 卷号: 135, 期号: 10, 页码: 2462-2474
作者:  Chen, Si-Meng;  Guo, Chen-Liang;  Shi, Jia-Jie;  Xu, Yi-Chao;  Chen, Yi
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
Systematic combination screening reveals synergism between rapamycin and sunitinib against human lung cancer 期刊论文
CANCER LETTERS, 2014, 卷号: 342, 期号: 1, 页码: 159-166
作者:  Li, Xian;  Tong, Lin-Jiang;  Ding, Jian;  Meng, Ling-Hua
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer 期刊论文
JOURNAL OF MOLECULAR MEDICINE-JMM, 2010, 卷号: 88, 期号: 9, 页码: 941-952
作者:  Chen, Guang;  Yang, Na;  Wang, Xiang;  Zheng, Si-Yuan;  Chen, Yi
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08


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