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A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:  Zhou, Jun;  Zhan, Yan;  Zhong, Dafang;  Chen, Xiaoyan;  Zhang, Yifan
收藏  |  浏览/下载:72/0  |  提交时间:2021/11/04
A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 9
作者:  Li, Zhen-wei;  Wei, Wen-long;  Li, Hao-jv;  Wu, Shi-fei;  Huang, Yong
收藏  |  浏览/下载:81/0  |  提交时间:2021/05/24
Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7
作者:  Pan, Lu-lu;  Chen, Tao;  Hui, Min;  Wang, Shuo;  Fu, Li
收藏  |  浏览/下载:131/0  |  提交时间:2021/05/24
Characterization and quantitative determination of henagliflozin metabolites in humans 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:  Chen, Zhendong;  Li, Liang;  Zhan, Yan;  Zhang, Yifan;  Liu, Haiyan
收藏  |  浏览/下载:20/0  |  提交时间:2021/05/24
UPLC-ESI-Q-TOF/MS Based Metabolic Profiling of Protosappanin B in Rat Plasma, Bile, Feces, Urine and Intestinal Bacteria Samples 期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 6, 页码: 491-499
作者:  Chen, Wei-Ying;  Liang, Guang-Yan;  Zheng, Zuo-Liang;  Wu, Yun-Shan;  Xu, Fang-Fang
收藏  |  浏览/下载:41/0  |  提交时间:2021/11/04
Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8
作者:  Zhang, Mengqi;  Liu, Haiming;  He, Jiajin;  Gui, Yuzhou;  Qian, Hongjie
收藏  |  浏览/下载:29/0  |  提交时间:2020/12/24
Direct quantification of anorethidrani disuccinate and determination of sterol metabolites by chemical derivatization combined with LC-MS/MS: Application to a Phase I pharmacokinetic study in humans 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1157, 页码: 9
作者:  Jiang, Jinfang;  Li, Liang;  Lu, Youming;  Chen, Yunhui;  Chen, Xiaoyan
收藏  |  浏览/下载:40/0  |  提交时间:2020/12/24
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:  Qiu, Yanan;  Tang, Chongzhuang;  Li, Ranran;  Cao, Sumin;  Zhang, Yuqiang
收藏  |  浏览/下载:28/0  |  提交时间:2020/12/24
Qualitative and quantitative determination of anaprazole and its major metabolites in human plasma 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 183, 页码: 10
作者:  Tang, Chongzhuang;  Li, Liang;  Ma, Xifeng;  Wang, Jin;  Chen, Bo
收藏  |  浏览/下载:82/0  |  提交时间:2020/07/01
Technologies to improve the sensitivity of existing chromatographic methods used for bioanalytical studies 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 卷号: 34, 期号: 3, 页码: 13
作者:  Chen, Zhendong;  Gao, Yuxiong;  Zhong, Dafang
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01


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