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科研机构
上海药物研究所 [80]
内容类型
期刊论文 [78]
会议论文 [1]
学位论文 [1]
发表日期
2021 [7]
2020 [1]
2019 [6]
2018 [8]
2017 [11]
2016 [7]
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Chemistry [4]
Pharmacolo... [3]
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Stereoselective Synthesis of beta-C-Glycosides of 3-Deoxy-D-manno-oct-2-ulosonic Acid (Kdo) via SmI2-Mediated Reformatsky Reactions
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 6090-6093
作者:
Zhang, Zhumin
;
Xu, Zhuojia
;
Liu, Xingbang
;
Luo, Shiwei
;
Li, Tiehai
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/11/04
Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 185, 页码: 14
作者:
Wu, Qian
;
Chen, Dan-Qi
;
Sun, Lin
;
Huan, Xia-Juan
;
Bao, Xu-Bin
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2021/05/24
N2817
Bivalent BET inhibitors
Monovalent BET inhibitors
TAF1
Anticancer activity
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:
Zhou, Yu
;
Li, Xiaoguang
;
Chen, Kerong
;
Ba, Qian
;
Zhang, Xu
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  |  
浏览/下载:38/0
  |  
提交时间:2021/06/11
Structural optimization
Lead compound
Artemisinin derivatives
Cancer
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:
Zhou, Yu
;
Li, Xiaoguang
;
Chen, Kerong
;
Ba, Qian
;
Zhang, Xu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
Structural optimization
Lead compound
Artemisinin derivatives
Cancer
Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:
Sun, Yin
;
Li, Na
;
Su, Mingbo
;
Wang, Xiaowen
;
Zhao, Dongmei
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  |  
浏览/下载:59/0
  |  
提交时间:2021/05/24
Divalent tranylcypromine
LSD1 inhibitor
MV4-11 antiproliferative activity
CD86 mRNA expression
Linker
Selectivity
Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective mu Opioid Receptor Agonists
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 2, 页码: 285-299
作者:
Huang, Huoming
;
Li, Xinwei
;
Guo, Wei
;
Zhu, Chen
;
Qian, Yuanyuan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
pain
opioid analgesic
SAR
selective MOR agonist
molecular dynamics simulations
Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2
期刊论文
BLOOD ADVANCES, 2021, 卷号: 5, 期号: 1, 页码: 185-197
作者:
Wu, Wenjun
;
Wang, Weige
;
Franzen, Carrie A.
;
Guo, Hui
;
Lee, Jimmy
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  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Co-Prodrugs of 7-Ethyl-10-hydroxycamptothecin and Vorinostat with in Vitro Hydrolysis and Anticancer Effects
期刊论文
ACS OMEGA, 2020, 卷号: 5, 期号: 1, 页码: 350-357
作者:
Liu, Shuangxi
;
Hu, Zonglong
;
Zhang, Qiumeng
;
Zhu, Qiwen
;
Chen, Yi
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  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Synthesis and Biological Evaluation of Five-Atom-Linker-Based Arylpiperazine Derivatives with an Atypical Antipsychotic Profile
期刊论文
CHEMMEDCHEM, 2019, 页码: 11
作者:
Wu, Chunhui
;
Wang, Yu
;
Yang, Feipu
;
Shi, Wenqiang
;
Wang, Zhen
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
D-2
5-HT1A
5-HT2A
serotonin
SERT
PCP-induced hyperactivity
Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling
期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 10, 页码: 1417-+
作者:
Jiang, Chenxiao
;
Tang, Yegen
;
Ding, Lulu
;
Tan, Renke
;
Li, Xiaojing
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
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