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CORC

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Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:  Gao, Dingding;  Jin, Nan;  Fu, Yixian;  Zhu, Yueyue;  Wang, Yujie
收藏  |  浏览/下载：43/0  |  提交时间：2021/06/11
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib 期刊论文
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:  Chen, Gege;  Hu, Ke;  Sun, Haiguo;  Zhou, Jinfeng;  Song, Dongliang
收藏  |  浏览/下载：97/0  |  提交时间：2020/07/01
A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11
作者:  Lu, Kang;  Li, Bo;  Zhang, Hui;  Xu, Zhijian;  Song, Dongliang
收藏  |  浏览/下载：58/0  |  提交时间：2020/07/01
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01
Xanthatin inhibits STAT3 and NF-kappa B signalling by covalently binding to JAK and IKK kinases 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 6, 页码: 4301-4312
作者:  Liu, Man;  Xiao, Cheng-qian;  Sun, Ming-wei;  Tan, Min-jia;  Hu, Li-hong
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01
Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 8, 页码: 3898-3923
作者:  Liang, Xuewu;  Zang, Jie;  Li, Xiaoyang;  Tang, Shuai;  Huang, Min
收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
3deoxy216dihydroxynagilactoneeanaturalcompoundfrompodocarpusnagipreferentiallyinhibitsjak2stat3signalingbyallostericallyinteractingwiththeregulatorydomainofjak2andinducesapoptosisofcancercells 期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 12, 页码: 1578
作者:  Shan Hui;  Yao Sheng;  Ye Yang;  Yu Qiang
收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01
3-Deoxy-2β,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/ STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
中国药理学报:英文版, 2019, 卷号: 40.0, 期号: 012, 页码: 1578
作者:  Hui Shan;  Sheng Yao;  Yang Ye;  Qiang Yu
收藏  |  浏览/下载：16/0  |  提交时间：2020/12/24
A natural compound derivative P-13 inhibits STAT3 signaling by covalently inhibiting Janus kinase 2 期刊论文
Investigational new drugs, 2018
作者:  
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 6
作者:  Liu, Man;  Xiao, Chengqian;  Sun, Mingwei;  Tan, Minjia;  Hu, Lihong
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08

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