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科研机构
上海药物研究所 [37]
内容类型
期刊论文 [36]
会议论文 [1]
发表日期
2021 [1]
2020 [1]
2018 [1]
2017 [2]
2016 [2]
2013 [7]
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A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 9
作者:
Li, Zhen-wei
;
Wei, Wen-long
;
Li, Hao-jv
;
Wu, Shi-fei
;
Huang, Yong
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/05/24
Metabolite profiling
Solid-phase extraction
Mass defect filter
Precursor ion list
Danqi Tongmai tablet
Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8
作者:
Zhang, Mengqi
;
Liu, Haiming
;
He, Jiajin
;
Gui, Yuzhou
;
Qian, Hongjie
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/24
TPN171
LC-MS/MS
Human plasma
Protein precipitation
Development of an LC-MS/MS-based assay to determine artemitin in rat plasma and its application in a pharmacokinetic study
期刊论文
Biomedical chromatography : BMC, 2018, 卷号: 32, 期号: 12, 页码: e4356
作者:
Han, Xiaoli
;
He, Jinhua
;
Chen, Qinyue
;
Sun, Yali
;
Zhang, Xiulei
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  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
A validated UPLC-MS/MS method coupled with protein precipitation and ion exchange solid phase extraction for the quantitation of porcine relaxin B29 in dog plasma and its application to a pharmacokinetic study
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2017, 卷号: 409, 期号: 28, 页码: 6559-6565
作者:
Su, Chong
;
Sun, Hui
;
Yang, Hong
;
Yin, Lei
;
Zhang, Jiwen
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
Ion exchange solid phase extraction
LC-MS/MS
Porcine relaxin
Ultrahigh performance liquid chromatography
Matrix Effects and Countermeasure of Liquid Chromatography-Tandem Mass Spectrometry in Bioanalysis
期刊论文
Journal of Chinese Mass Spectrometry Society, 2017, 卷号: 38, 期号: 4, 页码: 388-399
作者:
Liu, Xiao-Yun
;
Chen, Xiao-Yan
;
Zhong, Da-Fang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Nano-LC-ESI MS/MS analysis of proteins in dried sea dragon Solenognathus hardwickii and bioinformatic analysis of its protein expression profiling
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2016, 卷号: 14, 期号: 9, 页码: 709-713
作者:
Zhang Dong-Mei
;
Feng Li-Xing
;
Li Lu
;
Liu Miao
;
Jiang Bao-Hong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Sea dragon
Solenognathus hardwickii
Mass-spectrometry-based proteomics
Bioinformatic analysis
A simple method for quantification of tapentadol in dog plasma by liquid chromatography-tandem mass spectrometry and evaluation of the effects of conjugated metabolites on tapentadol
期刊论文
Acta Pharmaceutica Sinica, 2016, 卷号: 51, 期号: 3, 页码: 434-438
作者:
Liang Ge
;
Lu Youming
;
Dai Xiaojian
;
Qin Minjian
;
Zhong Dafang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
LC-MS/MS
LC-MS/MS
tapentadol
conjugated metabolite
pharmacokinetics
Development and validation of a sensitive LC-MS/MS assay for the simultaneous quantification of allitinib and its two metabolites in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013, 卷号: 86, 页码: 49-55
作者:
Lin, Lishan
;
Gao, Zhiwei
;
Chen, Xiaoyan
;
Zhong, Dafang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Liquid chromatography-tandem mass spectrometry
Allitinib
Metabolite
Pharmacokinetics
Human plasma
Pharmacokinetics of ganoderic acid D and its main metabolite by liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 卷号: 930, 页码: 1-6
作者:
Cheng, Chun-Ru
;
Yang, Min
;
Guan, Shu-Hong
;
Wu, Xiao-Hui
;
Pang, Xiao-Yan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Ganoderic acid D
Ganoderic acid B
LC/MS/MS
Nanoparticle
Pharmacokinetics
Triterpenoid
Structure features of polysaccharides from Chrysanthemum morifolium and their activities against tumor cells and NF-kappaB
期刊论文
Chinese Traditional and Herbal Drugs, 2013, 卷号: 44, 期号: 17, 页码: 2364-2371
作者:
Fan Lingjing
;
Ni Xinyan
;
Wu Chunjie
;
Ding Kan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
NF-kappaB
Chrysanthemum morifolium Ramat.
neutral polysaccharide
PANC-1 cell
LO2 cell
NF-kappaB
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