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科研机构
上海药物研究所 [35]
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期刊论文 [35]
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2021 [6]
2020 [4]
2019 [1]
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GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhang, Qing
;
Chen, Lin-hai
;
Yang, Hui
;
Fang, You-chen
;
Wang, Si-wei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/18
GPR84
medium chain fatty acid receptor
GPCR
inflammatory bowel diseases
ulcerative colitis
NLRP3 inflammasome
macrophages
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17
作者:
Li, Xinzhi
;
Yuan, Bingchuan
;
Lu, Min
;
Wang, Yuqin
;
Ding, Na
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/18
Quantitative proteomic analysis uncovers inhibition of melanin synthesis by silk fibroin via MITF/tyrosinase axis in B16 melanoma cells
期刊论文
LIFE SCIENCES, 2021, 卷号: 284, 页码: 7
作者:
Wang, Yuqiu
;
Duan, Tianbi
;
Hong, Minhua
;
Zhou, Yanting
;
Huang, Hui
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
Silk fibroin
Quantitative proteomics
Melanin
Microphthalmia-associated transcription factor
Tyrosinase
Acyl-CoA oxidase ACOX-1 interacts with a peroxin PEX-5 to play roles in larval development of Haemonchus contortus
期刊论文
PLOS PATHOGENS, 2021, 卷号: 17, 期号: 7, 页码: 21
作者:
Shi, Hengzhi
;
Huang, Xiaocui
;
Chen, Xueqiu
;
Yang, Yi
;
Wang, Zhao
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/11/04
A novel low systemic diacylglycerol acyltransferase 1 inhibitor, Yhhu2407, improves lipid metabolism
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 卷号: 158, 页码: 9
作者:
Huang, Jun-Shang
;
Guo, Bin-Bin
;
Lin, Fei-Fei
;
Zeng, Li-Min
;
Wang, Ting
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  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
DGAT1
Inhibitor
Pharmacokinetics
Dyslipidemia
Lipid metabolism
Quantitative proteomics reveals Shexiang Baoxin Pill exerts cardioprotective effects by preserving energy metabolism in a rat model of myocardial infarction
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 266, 页码: 10
作者:
Yu, Feng
;
Yu, Yue
;
Tian, Saisai
;
Zhou, Yanting
;
Chen, Xiangling
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/05/24
Shexiang baoxin pill
Cardiovascular disease
LC-MS/MS
Quantitative proteomics
Energy metabolism
DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Huang, Jun-shang
;
Guo, Bin-bin
;
Wang, Gai-hong
;
Zeng, Li-min
;
Hu, You-hong
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/12/24
type 2 diabetes
DGAT1 inhibitors
pancreatic beta-cells
apoptosis
ER stress
inflammation
Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway
期刊论文
CIRCULATION RESEARCH, 2020, 卷号: 127, 期号: 4, 页码: 534-549
作者:
You, Yan
;
Bao, Wei-Lian
;
Zhang, Su-Lin
;
Li, Hai-Dong
;
Li, Hui
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/12/24
atherosclerosis
foam cell
lipid metabolism
monocytes
sorting nexin
Effect of phosphatidylcholine on the stability and lipolysis of nanoemulsion drug delivery systems
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 卷号: 583, 页码: 9
作者:
Zhang, Bo
;
Zhou, Xin
;
Miao, Yunqiu
;
Wang, Xiaoli
;
Yang, Yuting
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/12/24
Phosphatidylcholine
Nanoemulsion
Stability
Lipolysis kinetics
Curcumin
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
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