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CORC

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Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:  Lu, Dasheng;  Liu, Yameng;  Luo, Yuhong;  Zhao, Jie;  Feng, Chao
收藏  |  浏览/下载：49/0  |  提交时间：2022/01/18
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:  Tang, Xuehang;  Ning, Mengmeng;  Ye, Yangliang;  Gu, Yipei;  Yan, Hongyi
收藏  |  浏览/下载：49/0  |  提交时间：2021/11/04
A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage 期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 120, 页码: 12
作者:  Huang, Suling;  Wu, Yanwei;  Zhao, Zhuohui;  Wu, Bing;  Sun, Kai
收藏  |  浏览/下载：88/0  |  提交时间：2021/08/17
miR-552-3p modulates transcriptional activities of FXR and LXR to ameliorate hepatic glycolipid metabolism disorder 期刊论文
JOURNAL OF HEPATOLOGY, 2021, 卷号: 74, 期号: 1, 页码: 8-19
作者:  Fan, Lei;  Lai, Rongtao;  Ma, Ningning;  Dong, Yunxia;  Li, Yu
收藏  |  浏览/下载：41/0  |  提交时间：2021/05/24
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:  Li, Junyou;  Liu, Mengqi;  Li, Yazhou;  Sun, Dan-dan;  Shu, Zhihao
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling 期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10
作者:  Xie, Zhifu;  Jiang, Haowen;  Liu, Wei;  Zhang, Xinwen;  Chen, Dakai
收藏  |  浏览/下载：32/0  |  提交时间：2020/12/21
Farnesoid X Receptor Constructs an Immunosuppressive Microenvironment and Sensitizes (FXRPD)-P-high-L1(low) NSCLC to Anti-PD-1 Immunotherapy 期刊论文
CANCER IMMUNOLOGY RESEARCH, 2019, 卷号: 7, 期号: 6, 页码: 990-1000
作者:  You, Wenjie;  Li, Lijun;  Sun, Deqiao;  Liu, Xueqing
收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01
18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway 期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:  Wu, Shou-Yan;  Cui, Shi-Chao;  Wang, Le;  Zhang, Yi-Ting;  Yan, Xiao-Xia
收藏  |  浏览/下载：93/0  |  提交时间：2019/01/08
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:  Wu, Shou-yan;  Cui, Shi-chao;  Wang, Le;  Zhang, Yi-ying;  Yan, Xiao-xia
收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01
HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1α promoter 期刊论文
Metabolism: clinical and experimental, 2018, 卷号: 85, 页码: 126-138
作者:  Xu, Xin;  Shi, Xiaofan;  Chen, Yidi;  Zhou, Tingting;  Wang, Jiaying
收藏  |  浏览/下载：69/0  |  提交时间：2019/01/08

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