CORC

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CORC

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Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:  Zhou, Yan;  Du, Dao-Hai;  Wang, Jia;  Cai, Xiao-Qing;  Deng, Alicia X.
收藏  |  浏览/下载：102/0  |  提交时间：2020/07/01
EZH2 inhibitors abrogate upregulation of trimethylation of H3K27 by CDK9 inhibitors and potentiate its activity against diffuse large B-cell lymphoma 期刊论文
HAEMATOLOGICA, 2020, 卷号: 105, 期号: 4, 页码: 1021-1031
作者:  Xie, Shao;  Wei, Fan;  Sun, Yi-ming;  Gao, Ying-lei;  Pan, Lu-lu
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01
Inhibition of Ezh2 In Vitro and the Decline of Ezh2 in Developing Midbrain Promote Dopaminergic Neurons Differentiation Through Modifying H3K27me3 期刊论文
STEM CELLS AND DEVELOPMENT, 2019, 卷号: 28, 期号: 10, 页码: 649-658
作者:  Hong, Feng;  Zhao, Mengxue;  Zhang, Lei;  Feng, Linyin
收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01
Deep Neural Network Classifier for Virtual Screening Inhibitors of (S)-Adenosyl-L-Methionine (SAM)-Dependent Methyltransferase Family 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 17
作者:  Li, Fei;  Wan, Xiaozhe;  Xing, Jing;  Tan, Xiaoqin;  Li, Xutong
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors 期刊论文
CELL, 2018, 卷号: 175, 期号: 1, 页码: 186-+
作者:  Huang, Xun;  Yan, Juan;  Zhang, Min;  Wang, Yafang;  Chen, Yi
收藏  |  浏览/下载：77/0  |  提交时间：2019/01/08
Structure of the PRC2 complex and application to drug discovery 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 963-976
作者:  Shi, Yi;  Wang, Xiao-xi;  Zhuang, You-wen;  Jiang, Yi;  Melcher, Karsten
收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08
Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 17, 页码: 3648-3661
作者:  Ye, Yan;  Zhang, Bidong;  Mao, Ruifeng;  Zhang, Chenhua;  Wang, Yulan
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
Histone lysine methyltransferases as anti-cancer targets for drug discovery 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1273-1280
作者:  Liu, Qing;  Wang, Ming-wei
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08

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