CORC

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CORC

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Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
收藏  |  浏览/下载：40/0  |  提交时间：2021/08/17
Development of Potent NEDD8-Activating Enzyme Inhibitors Bearing a Pyrimidotriazole Scaffold 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 9, 页码: 6161-6178
作者:  Xiong, Chaodong;  Zhou, Lina;  Tan, Jing;  Song, Shanshan;  Bao, Xubin
收藏  |  浏览/下载：32/0  |  提交时间：2021/08/17
A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:  Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong
收藏  |  浏览/下载：124/0  |  提交时间：2021/05/24
The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Hao, Bing-bing;  Li, Xiao-jing;  Jia, Xing-long;  Wang, Yu-xing;  Zhai, Lin-hui
收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01
pSILAC method coupled with two complementary digestion approaches reveals PRPF39 as a new E7070-dependent DCAF15 substrate 期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 210, 页码: 11
作者:  Jia, Xinglong;  Pan, Lulu;  Zhu, Mingrui;  Hu, Hao;  Zhai, Linhui
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01
DNA methylation modifier LSH inhibits p53 ubiquitination and transactivates p53 to promote lipid metabolism 期刊论文
EPIGENETICS & CHROMATIN, 2019, 卷号: 12, 期号: 1, 页码: 22
作者:  Chen, Ling;  Shi, Ying;  Liu, Na;  Wang, Zuli;  Yang, Rui
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
LSH  P53  DUB  PKM2  Lipid metabolism  
Deubiquitinase ubiquitin-specific protease 9X regulates the stability and function of E3 ubiquitin ligase ring finger protein 115 in breast cancer cells 期刊论文
CANCER SCIENCE, 2019, 卷号: 110, 期号: 4, 页码: 1268-1278
作者:  Lu, Qin;  Lu, Dayun
收藏  |  浏览/下载：58/0  |  提交时间：2020/07/01
Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 13
作者:  Han, Yamei;  Hu, Zhimin;  Cui, Aoyuan;  Liu, Zhengshuai;  Ma, Fengguang
收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 15, 页码: 6685-6704
作者:  Qin, Chong;  Hu, Yang;  Zhou, Bing;  Fernandez-Salas, Ester;  Yang, Chao-Yie
收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08
FBW7 is associated with prognosis, inhibits malignancies and enhances temozolomide sensitivity in glioblastoma cells 期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 4, 页码: 1001-1011
作者:  Lin, Jing;  Ji, Aihui;  Qiu, Guanzhong;  Feng, Huaizhi;  Li, Jian
收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08

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