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科研机构
上海药物研究所 [60]
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期刊论文 [58]
会议论文 [2]
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2018 [2]
2017 [2]
2016 [3]
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Characteristics of hERG and hNav1.5 channel blockade by sulcardine sulfate, a novel anti-arrhythmic compound
期刊论文
European journal of pharmacology, 2018, 卷号: 844, 页码: 130-138
作者:
Chen, Weihai
;
Gan, Lu
;
Wang, Yiping
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
A Statistical Thermodynamic Model for Ligands Interacting With Ion Channels: Theoretical Model and Experimental Validation of the KCNQ2 Channel
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Bai, Fang
;
Pi, Xiaoping
;
Li, Ping
;
Zhou, Pingzheng
;
Yang, Huaiyu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
KCNQ2 potassium channel
hill equation
thermodynamic model
patch clamp electrophysiology
activators
Identification of Intracellular beta-Barrel Residues Involved in Ion Selectivity in the Mechanosensitive Channel of Thermoanaerobacter tengcongensis
期刊论文
FRONTIERS IN PHYSIOLOGY, 2017, 卷号: 8
作者:
Song, Yingcai
;
Zhang, Bing
;
Guo, Fei
;
Yang, Maojun
;
Li, Yang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
TtMscS
anion selectivity
beta-barrel
selective filter
patch-clamp
single mutation
Structural insights into alternative splicing-mediated desensitization of jasmonate signaling
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 卷号: 114, 期号: 7, 页码: 1720-1725
作者:
Zhang, Feng
;
Ke, Jiyuan
;
Zhang, Li
;
Chen, Rongzhi
;
Sugimoto, Koichi
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
signaling
plant hormone
plant defense
plant pathogen
plant insect
Propofol inhibits hERG K+ channels and enhances the inhibition effects on its mutations in HEK293 cells
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2016, 卷号: 791, 页码: 168-178
作者:
Han, Sheng-Na
;
Jing, Ying
;
Yang, Lin-Lin
;
Zhang, Zhao
;
Zhang, Li-Rong
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  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Propofol
QT prolongation
Human ether-a-go-go-related gene (hERG)
Protein trafficking
Gene mutation
Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clamp-based high-throughput screening techniques
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 1, 页码: 105-110
作者:
Yue, Jin-feng
;
Qiao, Guan-hua
;
Liu, Ni
;
Chen, Xue-qin
;
Nan, Fa-jun
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
KCNQ2
channel activator
high-throughput screening
thallium flux assay
automated patch-clamp
ZG1732
ZG2083
Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clampbased high-throughput screening techniques
期刊论文
Acta Pharmacologica Sinica, 2016, 卷号: 37, 期号: 1, 页码: 105
作者:
Yue Jinfeng
;
Qiao Guanhua
;
Liu Ni
;
Chen Xueqin
;
Nan Fajun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
POTASSIUM CHANNEL
KV7 CHANNELS
EPILEPSY
IDENTIFICATION
GENE
KCNQ2
channel activator
high-throughput screening
thallium flux assay
automated patch-clamp
ZG1732
ZG2083
Development of Mechanostimulated Patch-Clamp System for Cellular Physiological Study
期刊论文
IEEE-ASME TRANSACTIONS ON MECHATRONICS, 2014, 卷号: 19, 期号: 4, 页码: 1138-1147
作者:
Zhang, Changlin
;
Li, Peng
;
Liu, Lianqing
;
Wang, Yuechao
;
Gao, Zhaobing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Atomic force microscope (AFM)
mechanosensitive (MS) ion channel
planar patch clamp
Design, Synthesis, and Structure-Activity Relationship Studies of Novel Fused Heterocycles-Linked Triazoles with Good Activity and Water Solubility
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 9, 页码: 3687-3706
作者:
Cao, Xufeng
;
Sun, Zhaoshuan
;
Cao, Yongbing
;
Wang, Ruilian
;
Cai, Tongkai
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Photobiomodulation on KATP Channels of Kir6.2-Transfected HEK-293 Cells
期刊论文
INTERNATIONAL JOURNAL OF PHOTOENERGY, 2014
作者:
Zhong, Fu-qing
;
Li, Yang
;
Mi, Xian-qiang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
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