CORC

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CORC

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Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:  Su, Haixia;  Yao, Sheng;  Zhao, Wenfeng;  Zhang, Yumin;  Liu, Jia
收藏  |  浏览/下载：30/0  |  提交时间：2021/08/17
Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure 期刊论文
VIROLOGY, 2009, 卷号: 388, 期号: 2, 页码: 324-334
作者:  Hu, Tiancen;  Zhang, Yu;  Li, Lianwei;  Wang, Kuifeng;  Chen, Shuai
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08
Design and synthesis of cinanserin analogs as severe acute respiratory syndrome coronavirus 3CL protease inhibitors 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2008, 卷号: 56, 期号: 10, 页码: 1400-1405
作者:  Yang, Qiangang;  Chen, Lill;  He, Xuchang;  Gao, Zhenting;  Bai, Donglu
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Residues on the dimer interface of SARS coronavirus 3C-like protease: Dimer stability characterization and enzyme catalytic activity analysis 期刊论文
JOURNAL OF BIOCHEMISTRY, 2008, 卷号: 143, 期号: 4, 页码: 525-536
作者:  Chen, Shuai;  Zhang, Jian;  Hu, Tiancen;  Chen, Kaixian;  Jiang, Hualiang
收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08
Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease - Crystal structure with molecular dynamics simulations 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 卷号: 283, 期号: 1, 页码: 554-564
作者:  Chen, Shuai;  Hu, Tiancen;  Zhang, Jian;  Chen, Jing;  Chen, Kaixian
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08
Design and synthesis of a novel fluorescent peptide substrate of SARS-CoV 3CL(pro) and studies on its enzymatic kinetics 期刊论文
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2007, 卷号: 28, 期号: 1, 页码: 79-82
作者:  Wan Hui-Xin;  Chen Li-Li;  Li Xin;  Wang Xin;  Hu Ding-Yu
收藏  |  浏览/下载：9/0  |  提交时间：2019/01/08
Binding interaction of quereetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): Structure-activity relationship studies reveal salient pharmacophore features 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 卷号: 14, 期号: 24, 页码: 8295-8306
作者:  Chen, Lili;  Li, Jian;  Luo, Cheng;  Liu, Hong;  Xu, Weijun
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08
Discovering severe acute respiratory syndrome coronavirus 3CL protease inhibitors: Virtual screening, surface plasmon resonance, and fluorescence resonance energy transfer assays 期刊论文
JOURNAL OF BIOMOLECULAR SCREENING, 2006, 卷号: 11, 期号: 8, 页码: 915-921
作者:  Chen, Lili;  Chen, Shuai;  Gui, Chunshan;  Shen, Jianhua;  Shen, Xu
收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08
Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro 期刊论文
JOURNAL OF VIROLOGY, 2005, 卷号: 79, 期号: 11, 页码: 7095-7103
作者:  Chen, LL;  Gui, CS;  Luo, XM;  Yang, QG;  Gunther, S
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08

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