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浏览/检索结果: 共2条，第1-2条 帮助 限定条件 专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation 期刊论文 ONCOTARGET, 2016 Wang, Aoli; Yan, Xiao-E; Wu, Hong; Wang, Wenchao; Hu, Chen; Chen, Cheng; Zhao, Zheng; Zhao, Peng; Li, Xixiang; Wang, Li; Wang, Beilei; Ye, Zi; Wang, Jinhua; Wang, Chu; Zhang, Wei; Gray, Nathanael S.; Weisberg, Ellen L.; Chen, Liang; Liu, Jing; Yun, Cai-Hong; Liu, Qingsong 收藏  |  浏览/下载：2/0  |  提交时间：2017/12/04 Ibrutinib  EGFR kinase  DFG-in/c-Helix-out  inactive conformation  NSCLC  BRUTONS TYROSINE KINASE  MANTLE-CELL LYMPHOMA  CHRONIC LYMPHOCYTIC-LEUKEMIA  GROWTH-FACTOR RECEPTOR  INHIBITORS  BTK  SYSTEM  CRYSTALLOGRAPHY  ACTIVATION  RESISTANCE   Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells 期刊论文 ONCOTARGET, 2015 Wu, Hong; Wang, Aoli; Zhang, Wei; Wang, Beilei; Chen, Cheng; Wang, Wenchao; Hu, Chen; Ye, Zi; Zhao, Zheng; Wang, Li; Li, Xixiang; Yu, Kailin; Liu, Juan; Wu, Jiaxin; Yan, Xiao-E; Zhao, Peng; Wang, Jinhua; Wang, Chu; Weisberg, Ellen L.; Gray, Nathanael S.; Yun, Cai-Hong; Liu, Jing; Chen, Liang; Liu, Qingsong 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 ibrutinib  NSCLC  EGFR mutation  drug resistance  drug combination  GROWTH-FACTOR RECEPTOR  BRUTONS TYROSINE KINASE  CHRONIC LYMPHOCYTIC-LEUKEMIA  LUNG-CANCER  ACQUIRED-RESISTANCE  INHIBITORS  BTK  MUTATION  GEFITINIB  LYMPHOMA