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科研机构
北京大学 [49]
内容类型
期刊论文 [39]
其他 [10]
发表日期
2017 [2]
2016 [2]
2015 [1]
2014 [2]
2013 [2]
2012 [1]
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专题:北京大学
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Stress ulcer prophylaxis in the intensive care unit trial: detailed statistical analysis plan
其他
2017-01-01
Krag, M.
;
Perner, A.
;
Wetterslev, J.
;
Lange, T.
;
Wise, M. P.
;
Borthwick, M.
;
Bendel, S.
;
Pelosi, P.
;
Keus, F.
;
Guttormsen, A. B.
;
Schefold, J. C.
;
Meyhoff, T. S.
;
Marker, S.
;
Moller, M. H.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/12/03
PROTON-PUMP INHIBITORS
CLOSTRIDIUM-DIFFICILE INFECTION
CRITICALLY-ILL PATIENTS
RANDOMIZED CONTROLLED-TRIAL
2 RECEPTOR ANTAGONISTS
III PATIENTS
METAANALYSIS
RISK
CLOPIDOGREL
OUTCOMES
Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses
期刊论文
JOURNAL OF NEUROSCIENCE, 2017
Lee, Sung-Jin
;
Wei, Mengping
;
Zhang, Chen
;
Maxeiner, Stephan
;
Pak, ChangHui
;
Botelho, Salome Calado
;
Trotter, Justin
;
Sterky, Fredrik H.
;
Sudhof, Thomas C.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
AMPAR
cell adhesion molecule
neuronal pentraxin receptor
synaptogenesis
DEVELOPING VISUAL-SYSTEM
AMPA RECEPTORS
TERMINAL DOMAIN
NARP
NEUREXINS
NEUROLIGINS
PLASTICITY
NP1
DIFFERENTIATION
INTERNEURONS
On the Eve of Upgrading Antidepressants: (R)-Ketamine and Its Metabolites
期刊论文
NEUROSCIENCE BULLETIN, 2016
Yuan, Kai
;
Han, Ying
;
Hashimoto, Kenji
;
Lu, Lin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
Upgrading
Antidepressants
(R)-Ketamine
RAPID-ACTING ANTIDEPRESSANTS
SUSTAINED ANTIDEPRESSANT
R-KETAMINE
NMDA ANTAGONISTS
MAJOR DEPRESSION
MECHANISMS
ONSET
PLASTICITY
RECEPTORS
TRIAL
De novo design of helical peptides to inhibit tumor necrosis factor-alpha by disrupting its trimer formation
期刊论文
MEDCHEMCOMM, 2016
Shen, Qi
;
Zhang, Changsheng
;
Liu, Hongbo
;
Liu, Yuting
;
Cao, Junyue
;
Zhang, Xiaolin
;
Liang, Yuan
;
Zhao, Meiping
;
Lai, Luhua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
SMALL-MOLECULE INHIBITORS
TNF-ALPHA
FACTOR ANTAGONISTS
BINDING
OLIGOMERIZATION
SUPERFAMILY
RECEPTORS
DISCOVERY
DOMAIN
Bcl-2 Antagonists Kill Plasmacytoid Dendritic Cells From Lupus-Prone Mice and Dampen Interferon-alpha Production
期刊论文
arthritis rheumatology, 2015
Zhan, Yifan
;
Carrington, Emma M.
;
Ko, Hyun-Ja
;
Vikstrom, Ingela B.
;
Oon, Shereen
;
Zhang, Jian-Guo
;
Vremec, David
;
Brady, Jamie L.
;
Bouillet, Philippe
;
Wu, Li
;
Huang, David C. S.
;
Wicks, Ian P.
;
Morand, Eric F.
;
Strasser, Andreas
;
Lew, Andrew M.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
AUTOIMMUNE-DISEASE
NUCLEIC-ACIDS
BH3 MIMETICS
TH17 CELLS
IFN-ALPHA
T-CELL
ERYTHEMATOSUS
PATHOGENESIS
EXPRESSION
PROTEINS
Discovery of highly potent TNF alpha inhibitors using virtual screen
期刊论文
欧洲医药化学杂志, 2014
Shen, Qi
;
Chen, Jing
;
Wang, Qian
;
Deng, Xiaobing
;
Liu, Ying
;
Lai, Luhua
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2015/11/11
TNF alpha
Virtual screen
Small molecule inhibitors
TUMOR-NECROSIS-FACTOR
SMALL-MOLECULE INHIBITORS
PROMISCUOUS INHIBITORS
FACTOR ANTAGONISTS
SURAMIN
OLIGOMERIZATION
SUPERFAMILY
GENERATION
DOCKING
BINDING
Identification and functional validation of novel TRPV3 antagonists from natural product derivatives
其他
2014-01-01
张碧晨
;
张浩
;
李蒙
;
付宏征
;
王克威
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
permeable
bottleneck
gated
sensation
validation
physiology
clamp
screening
amplifier
throughput
permeable
bottleneck
gated
sensation
validation
physiology
clamp
screening
amplifier
throughput
Interactive effects of morphine and dopaminergic compounds on spatial working memory in rhesus monkeys
期刊论文
神经科学通报, 2013
Wang, Jian-Hong
;
Rizak, Joshua Dominie
;
Chen, Yan-Mei
;
Li, Liang
;
Hu, Xin-Tian
;
Ma, Yuan-Ye
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/12
working memory
morphine
dopamine
rhesus monkey
PREFRONTAL CORTEX
SYNAPTIC PLASTICITY
NUCLEUS-ACCUMBENS
MOTOR CONTROL
AGED MONKEYS
RECEPTOR
AVOIDANCE
NALOXONE
TASK
MICE
One-Pot Syntheses of Isoquinolin-3-ones and Benzo-1,4-diazepin-2,5-diones Utilizing Ugi-4CR Post-Transformation Strategy
期刊论文
acs combinatorial science, 2013
Che, Chao
;
Li, Song
;
Yu, Zhixiong
;
Li, Fangfang
;
Xin, Shengchang
;
Zhou, Liyan
;
Lin, Shuo
;
Yang, Zhen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/14
isoquinolin-3-ones
benzo-1,4-diazepin-2,5-diones
multicomponent reaction
Ugi-4CR
one-pot synthesis
diversity-oriented synthesis
MULTICOMPONENT REACTIONS
BIOLOGICAL EVALUATION
HDM2 ANTAGONISTS
DRUG DISCOVERY
INHIBITORS
DERIVATIVES
CHEMISTRY
DESIGN
UGI
1,4-BENZODIAZEPINE-2,5-DIONES
吲哚哌啶-哌嗪类衍生物在α1-肾上腺素受体介导的收缩反应中的生物学活性
期刊论文
中国药理学与毒理学杂志, 2012
李素芳
;
刘飞
;
刘巍
;
赵悦
;
吕志珍
;
徐明
;
张幼怡
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2015/11/12
受体,肾上腺素 α1肾上腺素受体拮抗剂 吲哚哌啶-哌嗪衍生物 adrenoceptor α1 -adrenoceptor antagonists indolylpiperidine-piperazine derivatives
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