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科研机构
北京大学 [9]
内容类型
期刊论文 [9]
发表日期
2015 [3]
2013 [2]
2011 [3]
2003 [1]
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专题:北京大学
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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
期刊论文
NATURE, 2015
Shi, Jianjin
;
Zhao, Yue
;
Wang, Kun
;
Shi, Xuyan
;
Wang, Yue
;
Huang, Huanwei
;
Zhuang, Yinghua
;
Cai, Tao
;
Wang, Fengchao
;
Shao, Feng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
III SECRETION APPARATUS
BACTERIAL FLAGELLIN
NLRC4 INFLAMMASOME
INTRACELLULAR LPS
ACTIVATION
MECHANISMS
RECEPTORS
IMMUNITY
Divergent roles of BECN1 in LC3 lipidation and autophagosomal function
期刊论文
autophagy, 2015
He Ruina
;
Peng Jingyu
;
Yuan Pengfei
;
Xu Fang
;
Wei Wensheng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2015/11/11
ATG, autophagy related,BCL2L1/Bcl-xL, BCL2-like 1,BECN1,BECN1, beclin 1, autophagy related,BECN1P1/BECN2, beclin 1, autophagy related, pseudogene 1,BafA1, bafilomycin A1,EM, electron microscopy,FYVE domain containing 1,GAPDH, glyceraldehyde-3-phosphate dehydrogenase,GFP, green fluorescent protein,KO, knockout,LC3,MAP1LC3-I/LC3-I, soluble, proteolytically processed microtubule-associated protein 1 light chain 3,MAP1LC3-II/LC3-II, proteolytically processed and lipid-modified microtubule-associated protein 1 light chain 3,MAP1LC3/LC3, microtubule-associated protein 1 light chain 3,MAP1LC3B/LC3B, microtubule-associated protein 1 light chain 3 beta,PIK3C3/VPS34, phosphatidylinositol 3-kinase, catalytic subunit type 3,PIK3R4/VPS15, phosphoinositide-3-kinase, regulatory subunit 4,PtdIns3K,PtdIns3K, phosphatidylinositol 3-kinase,SQSTM1/p62, sequestosome 1,TALEN, transcription activator-like effector nuclease,TUBB, tubulin, beta class I,UVRAG, UV radiation resistance associated,ZFYVE1/DFCP1, zinc finger,autophagosome,autophagy
Creating a monomeric endonuclease TALE-I-SceI with high specificity and low genotoxicity in human cells
期刊论文
核酸研究, 2015
Lin, Jianfei
;
Chen, He
;
Luo, Ling
;
Lai, Yongrong
;
Xie, Wei
;
Kee, Kehkooi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/13
ZINC-FINGER NUCLEASES
HISTONE H2AX PHOSPHORYLATION
GENE-THERAPY
MAMMALIAN-CELLS
CAS9
ARCHITECTURE
SYSTEMS
REPAIR
BREAKS
Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability
期刊论文
proceedings of the national academy of sciences of the united states of america, 2013
Wang, Donglai
;
Zhou, Jingyi
;
Liu, Xiangyu
;
Lu, Danyu
;
Shen, Changchun
;
Du, Yipeng
;
Wei, Fu-Zheng
;
Song, Boyan
;
Lu, Xiaopeng
;
Yu, Yu
;
Wang, Lina
;
Zhao, Ying
;
Wang, Haiying
;
Yang, Yang
;
Akiyama, Yoshimitsu
;
Zhang, Hongquan
;
Zhu, Wei-Guo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
histone methylation
nonhistone posttranslational modifications
DNA-DAMAGE RESPONSE
HISTONE H3 METHYLATION
LYSINE METHYLATION
TRANSFERASE SUV39H1
TUMOR SUPPRESSION
P53 ACTIVITY
METHYLTRANSFERASE
CHROMATIN
SIRT1
HP1
TALEN 构建与斑马鱼基因组定点突变的实验方法与流程
期刊论文
遗传, 2013
沈延
;
黄鹏
;
张博
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
类转录激活因子效应物核酸酶(TALEN) 斑马鱼 基因组定点突变 基因打靶 反向遗传学技术
Domain-Specific Folding Kinetics of Staphylococcal Nuclease Observed through Single-Molecule FRET in a Microfluidic Mixer
期刊论文
chemphyschem, 2011
Zhi, Zeyong
;
Liu, Pengcheng
;
Wang, Peng
;
Huang, Yanyi
;
Zhao, Xin Sheng
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2015/11/13
FRET
microfluidic mixer
proteins
single-molecule studies
SNase
CIRCULAR-DICHROISM
PROTEIN COLLAPSE
SPECTROSCOPY
FLUORESCENCE
STATES
人工锌指核酸酶介导的基因组定点修饰技术
期刊论文
遗传, 2011
肖安
;
胡莹莹
;
王唯晔
;
杨志芃
;
王展翔
;
黄鹏
;
佟向军
;
张博
;
林硕
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2015/10/23
锌指核酸酶
锌指蛋白
基因组定点修饰
基因打靶
分子工具
Alternative split sites for fragment complementation, and glyphosate function as extra ligand and stabilizer for the AroA enzyme complexes
期刊论文
科学通报 英文版, 2011
Li Yan
;
Sun YiCheng
;
Yan HaiQin
;
Wang YiPing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
AroA
fragment complementation
glyphosate
extra ligand
complex stability
3-PHOSPHATE SYNTHASE
ESCHERICHIA-COLI
STAPHYLOCOCCAL NUCLEASE
HERBICIDE GLYPHOSATE
PEPTIDE-FRAGMENTS
PROTEIN
RECONSTITUTION
INHIBITOR
TOLERANCE
DOMAIN
Expression, purification, crystallization of fragments from the C-terminal region of DFF45/ICAD
期刊论文
acta crystallographica section d biological crystallography, 2003
Ding, H
;
Qiu, SH
;
Li, SL
;
Symersky, J
;
Green, TJ
;
Luo, M
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/14
CASPASE-ACTIVATED DNASE
DFF40
DOMAIN
CHAPERONE
APOPTOSIS
INHIBITOR
NUCLEASE
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