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浏览/检索结果: 共4条，第1-4条 帮助 限定条件 专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation 期刊论文 ONCOTARGET, 2016 Wang, Aoli; Yan, Xiao-E; Wu, Hong; Wang, Wenchao; Hu, Chen; Chen, Cheng; Zhao, Zheng; Zhao, Peng; Li, Xixiang; Wang, Li; Wang, Beilei; Ye, Zi; Wang, Jinhua; Wang, Chu; Zhang, Wei; Gray, Nathanael S.; Weisberg, Ellen L.; Chen, Liang; Liu, Jing; Yun, Cai-Hong; Liu, Qingsong 收藏  |  浏览/下载：2/0  |  提交时间：2017/12/04 Ibrutinib  EGFR kinase  DFG-in/c-Helix-out  inactive conformation  NSCLC  BRUTONS TYROSINE KINASE  MANTLE-CELL LYMPHOMA  CHRONIC LYMPHOCYTIC-LEUKEMIA  GROWTH-FACTOR RECEPTOR  INHIBITORS  BTK  SYSTEM  CRYSTALLOGRAPHY  ACTIVATION  RESISTANCE   A Mathematical Model of Fas Signaling Induced Apoptosis 其他 2010-01-01 Gu, Chang; Zhang, Junjie; Chen, Yingyu; Lei, Jinzhi 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/13 Mathematical Model  Caspase-3  Caspase-8  Bistability  P53-INDUCED APOPTOSIS  CASPASE-3 ACTIVATION  BISTABILITY  DEGRADATION  INHIBITORS  CD95   Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase 期刊论文 current pharmaceutical design, 2006 Lai, Luhua; Han, Xiaofeng; Chen, Hao; Wei, Ping; Huang, Changkang; Liu, Shiyong; Fan, Keqiang; Zhou, Lu; Liu, Zhenming; Pei, Jianfeng; Liu, Ying 收藏  |  浏览/下载：5/0  |  提交时间：2015/11/13 SARS 3C-like proteinase  quaternary structure  enzyme catalytic mechanism  substrate selectivity  inhibitor design  ACUTE RESPIRATORY SYNDROME  RHINOVIRUS 3C PROTEASE  CORONAVIRUS MAIN PROTEINASE  IMIDAZOLIUM ION-PAIR  ACTIVE-SITE  2-PYRIDONE-CONTAINING PEPTIDOMIMETICS  ANALYTICAL ULTRACENTRIFUGATION  IRREVERSIBLE INHIBITORS  BIOLOGICAL EVALUATION  GENOME SEQUENCE   Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors 期刊论文 journal of medicinal chemistry, 2006 Zhou, Lu; Liu, Ying; Zhang, Weilin; Wei, Ping; Huang, Changkang; Pei, Jianfeng; Yuan, Yaxia; Lai, Luhua 收藏  |  浏览/下载：2/0  |  提交时间：2015/11/11 ACUTE RESPIRATORY SYNDROME  MAIN PROTEINASE  3CL PROTEASE  DESIGN  IDENTIFICATION  3CL(PRO)  MECHANISM  COMPLEX  COV