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山东大学 [18]
西安交通大学 [13]
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复旦大学上海医学院 [8]
上海药物研究所 [6]
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期刊论文 [107]
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Shabyar Ameliorates High Glucose Induced Retinal Pigment Epithelium Injury Through Suppressing Aldose Reductase and AMPK/mTOR/ULK1 Autophagy Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 期号: 5, 页码: 1-15
作者:
Liu, XY (Liu, Xiao Yan) [1] , [2] , [3]
;
Peng, J (Peng, Jun) [1] , [2]
;
He, F (He, Fei) [1]
;
Tursun, X (Tursun, Xirali) [4]
;
Li, SP (Li, Shu Ping) [1]
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2022/06/06
shabyar
retinal pigment epithelium
autophagy
aldose reductase
traditional medicine formula
Transplantation of GMP-grade human iPSC-derived retinal pigment epithelial cells in rodent model: the first pre-clinical study for safety and efficacy in China
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9
作者:
Zhang, Hang
;
Su, Bingnan
;
Jiao, Luyan
;
Xu, Ze-Hua
;
Zhang, Chang-Jun
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/31
GMP grade
human iPSCs
RPE cells
pre-clinical study
transplantation
tumorigenicity
High-glucose induces retinal pigment epithelium mitochondrial pathways of apoptosis and inhibits mitophagy by regulating ROS/PINK1/Parkin signal pathway
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 111
作者:
Zha, Xu
;
Zhang, Yuanping
;
Xi, Xiaoting
;
Mei, Yan
;
Zhao, Xueying
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/04
Diabetic retinopathy
High-glucose
Mitophagy
Apoptosis
RPE
Abnormal mTORC1 signaling leads to retinal pigment epithelium degeneration
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 4
作者:
Huang, Jiancheng
;
Gu, Shun
;
Chen, Meng
;
Zhang, Shu-jie
;
Jiang, Zhichun
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/12/05
RPE degeneration
mTORC1
metabolism
Proline mediates metabolic communication between retinal pigment epithelial cells and the retina
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 26
作者:
Yam, Michelle
;
Engel, Abbi L.
;
Wang, Yekai
;
Zhu, Siyan
;
Hauer, Allison
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/12/05
retinal metabolism
amino acid
mitochondrial metabolism
tricarboxylic acid cycle (TCA cycle) (Krebs cycle)
cell metabolism
age-related macular degeneration (AMD)
glucose metabolism
oxidative stress
visual function
proline
retinal pigment epithelium
retina
Autophagy Promotes the Expression of Vascular Endothelial Growth Factor in Human Retinal Pigment Epithelium Cells
期刊论文
ANALYTICAL AND QUANTITATIVE CYTOPATHOLOGY AND HISTOPATHOLOGY, 2019, 卷号: 41, 页码: 16-22
作者:
Chai, Xinhong
;
Li, Xia
;
Kang, Mengyang
;
Wang, Xiaoye
;
Du, Junhui
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/11/19
Beclin-1
vision loss
VEGF
neovascularization
autophagy
vascular endothelial growth factor
hypoxia
retinal pigment epithelial
hypoxia in vitro
intraocular neovascularization
choroidal neovas-cularization
ophthalmic diseases
A derivative of betulinic acid protects human Retinal Pigment Epithelial cells from cobalt chloride-induced acute hypoxic stress
期刊论文
Experimental Eye Research, 2019, 卷号: Vol.180, 页码: 92-101
作者:
Zhengqi Cheng
;
Wenjuan Yao
;
Jian Zheng
;
Weimin Ding
;
Yang Wang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/02/25
Retinal
Pigment
Epithelium
Betulinic
acid
Cobalt
chloride
Hypoxic
stress
Signaling
pathways
Abnormal mTORC1 signaling leads to retinal pigment epithelium degeneration
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 4, 页码: 1170-1180
作者:
Huang, Jiancheng
;
Gu, Shun
;
Chen, Meng
;
Zhang, Shu-jie
;
Jiang, Zhichun
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/11
RPE degeneration
mTORC1
metabolism
Amphiregulin and ocular axial length
期刊论文
ACTA OPHTHALMOLOGICA, 2019, 卷号: 97, 期号: 3, 页码: E460-E470
作者:
Dong, Li
;
Shi, Xu Han
;
Kang, Yi Kun
;
Wei, Wen Bin
;
Wang, Ya Xing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/11
amphiregulin
blindness
Bruch ' s membrane
epidermal growth factor
myopia
myopic retinopathy
refractive error
retinal pigment epithelium
Scutellarin protects human retinal pigment epithelial cells against hydrogen peroxide -induced oxidative damage.
期刊论文
Cell & bioscience, 2019, 页码: 12
作者:
Xin Hu
;
Xiaofang Wu
;
Bo Zhao
;
Yongyi Wang
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/17
JAK2/STAT3
signaling
pathway
Oxidative
stress
Proliferative
vitreoretinopathy
(PVR)
Retinal
pigment
epithelium
(RPE)
cells
Scutellarin
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