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Compounds tetrahydropyrido-pyridine derivatives and tetrahydropyrido-pyrimidine, receptor modulators c5a; pharmaceutical composition comprising the same; pharmaceutical combination; use in the treatment of age-related macular degeneration, diabetic retinopathy, multiple sclerosis, bird, parkinson' s disease, crohn' s disease, among others. 专利
作者:  GELIN CHRISTINE;  ALEC FLYER;  CHRISTOPHER MICHAEL ADAMS;  VERONIQUE DARSIGNY;  TIMOTHY BRIAN HURLEY
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New dihydro-1H-imidazo(1, 2-a)pyrimidin-5-one compounds are Vps34 inhibitors useful for treating e.g. fibrotic disorders, mesangial cell proliferation disorders, metabolic disorders, allergies, asthma, thrombosis, retinopathy and psoriasis 专利
作者:  ARIGON JEROME;  BROLLO MAURICE;  CLEMENT JACQUES;  EL AHMAD YOUSSEF;  LABROSSE JEAN ROBERT
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New pyrimidinone compounds are akt phosphorylation inhibitors useful for treating e.g. thyroid cancer, allergies, asthma, thrombosis, nervous system diseases, retinopathy, psoriasis, rheumatoid arthritis, diabetes and muscle degeneration 专利
作者:  BROLLO MAURICE;  CARRY JEAN-CHRISTOPHE;  CERTAL VICTOR;  DIDIER ERIC;  DOERFLINGER GILLES
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Compounds thiazoloderivatives-pyrimidine-urea, antiparasitic receptor active adenosine a2b; pharmaceutical composition comprising such compounds; and their use of the compound in the treatment and prophylaxis of diabetes, asthma and diarrhea retinopathy. 专利
作者:  FARIBORZ FIROOZNIA;  KEVIN RICHARD GUERTIN;  LIDA QI;  JOHN A BRINKMAN;  ADRIAN WAI-HING CHEUNG
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COMPOUND PHARMACEUTICAL COMPOSITION, THERAPEUTIC METHOD FOR TREATING A PATHOLOGICAL CONDITION OR A SYMPTOM IN A MAMMAL, METHOD FOR THE TREATMENT OF ASTHMA, ALLERGIES, ALLERGIC DISEASES OR AN AUTOIMMUNE DISEASE, METHOD FOR TREATING DIARRHEAL DISEASES, INSULIN RESISTANCE, DIABETES MANAGEMENT, CANCER, ISCHEMIA/REPERFUSION WOUNDS, DIABETIC RETINOPATHY OR HYPERBARIC OXYGEN-INDUCED [...] AND FOR 专利
作者:  WANG GUOQUAN;  THOMPSON ROBERT D
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New heterocyclyl substituted triazolo(4, 3-b)pyridazine compounds are Met protein kinase inhibitors useful to treat e.g. allergies, asthma, thrombosis, retinopathy, psoriasis, rheumatoid arthritis, diabetes, muscle degeneration and cancer 专利
作者:  ALBERT EVA;  BACQUE ERIC;  NEMECEK CONCEPTION;  UGOLINI ANTONIO;  WENTZLER SYLVIE
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New 6-triazolopyridazine-sulfanyl benzothiazole compounds are met kinase inhibitors useful for treating e.g. metabolic disorders, allergies, asthma, thrombosis, nervous system diseases, retinopathy, psoriasis, diabetes and cancers 专利
作者:  BACQUE ERIC;  DAMOUR DOMINIQUE;  NEMECEK CONCEPTION;  UGOLINI ANTONIO;  WENTZLER SYLVIE
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