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兰州大学 [15]
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期刊论文 [15]
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2017 [1]
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pharmacol... [15]
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学科主题:pharmacology & pharmacy
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Design and optimization of thermosensitive nanoemulsion hydrogel for sustained-release of praziquantel
期刊论文
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2017, 卷号: 43, 期号: 1-4, 页码: 558-573
作者:
Cong, ZT
;
Wei, B
;
Wang, Y
;
Li, JC
;
Li, JY
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/05/09
Praziquantel
nanoemulsion
hydrogel
Box-Behnken design
cytotoxicity
pharmacokinetics
Effects of probenecid and cimetidine on the pharmacokinetics of nemonoxacin in healthy Chinese volunteers
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2016, 卷号: 10, 页码: 357-370
作者:
Zhang, YF
;
Dai, XJ
;
Yang, Y
;
Chen, XY
;
Wang, T
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/01/09
nemonoxacin
probenecid
cimetidine
clinical pharmacokinetics
drug-drug interaction
Studies on the IC50 of Trisubstituted Thiazoles as Cdc7 Kinase Inhibitors
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 1, 页码: 33-42
作者:
Yang, HZ
;
Liu, X
;
Ye, ZL
;
Song, FC
;
Cui, LH
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/01/11
Gene expression programming
IC50
kinase inhibitors
quantitative structure activity relationship
cell division cycle 7
trisubstituted thiazoles
A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2015, 卷号: 9, 页码: 2947-2959
作者:
Zhang, YH
;
Sun, XL
;
Huang, M
;
Ke, YQ
;
Wang, JH
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/01/09
bispecific immunotoxin
human mesenchymal stem cells
ephrin A1
VEGF(165)
malignant glioma
QSAR Modeling for the Antimalarial Activity of 1,4-Naphthoquinonyl Derivatives as Potential Antimalarial Agents
期刊论文
CURRENT COMPUTER-AIDED DRUG DESIGN, 2013, 卷号: 9, 期号: 1
-
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2014/12/05
Antimalarial activity
dug design
malaria
molecular design
multiple linear regression (MLR)
1,4-Naphthoquinonyl derivatives
QSAR
radial basis function neural network (RBFNN)
QSAR Studies of PTP1B Inhibitors: 1, 2-Naphthoquinone Derivatives
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2012, 卷号: 9, 期号: 10
-
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2014/12/05
Diabetes mellitus
Multiple linear regression (MLR)
1, 2-naphoquinone derivatives
Protein tyrosine phosphatase 1B (PTP1B)
Quantitative structure-activity relationships (QSAR)
Radial basis function neural networks (RBFNN)
QSAR Studies of PTP1B Inhibitors: Recent Advances and Perspectives
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2012, 卷号: 19, 期号: 25
-
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2014/12/05
Diabetes mellitus
protein tyrosine phosphatase 1B inhibitors
type 2 diabetes
drug design
virtual screening
quantitative structure-activity relationships (QSAR)
3D-QSAR
comparative molecular field analysis (CoMFA)
comparative molecular similarity indices analysis (CoMSIA)
2D-QSAR
multiple linear regression (MLR)
radial basis function neural networks (RBFNN)
The Evolution of HLA-B*3501 Binding Affinity to Variable Immunodominant NP418-426 Peptides from 1918 to 2009 Pandemic Influenza A Virus: A Molecular Dynamics Simulation and Free Energy Calculation Study
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2012, 卷号: 79, 期号: 6
-
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2014/12/05
2009 influenza A virus
HLA-B*3501
molecular dynamics simulation
NP418-426
pMHC-I
Study on the Anticancer Activity of Coumarin Derivatives by Molecular Modeling
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2011, 卷号: 78, 期号: 4
-
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2014/12/05
anticancer activity
CoMFA
CoMSIA
coumarin
docking
protein kinase 2
Study of Human Dopamine Sulfotransferases Based on Gene Expression Programming
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2011, 卷号: 78, 期号: 3
-
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2014/12/05
gene expression programming
heuristic method
Km
quantitative structure-activity relationship
sulfotransferases
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