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上海药物研究所 [9]
昆明植物研究所 [7]
南海海洋研究所 [4]
兰州大学 [3]
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期刊论文 [32]
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Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxytryptamine 2C receptor from Bupleurum chinense and their potential use for the treatment of obesity
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 6, 页码: 467-473
作者:
Sun Chang-Li
;
Geng Chang-An
;
Huang Xiao-Yan
;
Ma Yun-Bao
;
Zheng Xiao-Hong
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2017/10/23
Bupleurum Chinense
5-hydroxytryptamine 2c (5-ht2c) Receptor
Anti-obesity
Saikosaponins
Nitric oxide production inhibition and mechanism of phenanthrene analogs in lipopolysaccharide-stimulated RAW264.7 macrophages
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 10, 页码: 2521-2525
作者:
Yuan, XH (reprint author), Southwest Univ Sci & Technol, Sch Life Sci & Engn, Mianyang, Peoples R China.
;
Chen, LQ
;
Shen, XF
;
Hu, BY
;
Lin, Y
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  |  
浏览/下载:26/0
  |  
提交时间:2017/11/09
Phenanthrene
Anti-inflammatory Activity
P38
Ijba
Macrophage
Structure-Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4-Methylester-Rakicidin A
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 3, 页码: 1184-1196
作者:
Yang, Guang
;
Zhang, Quan
;
Chen, Yue
;
Sang, Feng
;
Ding, Yahui
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  |  
浏览/下载:25/0
  |  
提交时间:2018/12/13
Structure-Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4-Methylester-Rakicidin A
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 3, 页码: 1184-1196
Sang, Feng
;
Ding, Yahui
;
Wang, Jinghan
;
Sun, Bingxia
;
Sun, Jianlei
;
Geng, Yan
;
Zhang, Zhang
;
Ding, Ke
;
Wu, Ling-Ling
;
Liu, Jian-Wei
;
Ba, Cuigai
;
Yang, Guang
;
Zhang, Quan
;
Li, Lu-Yuan
;
Chen, Yue
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  |  
浏览/下载:46/0
  |  
提交时间:2016/12/16
Ligand Efficiency Outperforms pIC(50) on Both 2D MLR and 3D CoMFA Models: A Case Study on AR Antagonists
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 6, 页码: 1501-1517
作者:
Li, JZ
;
Bai, F
;
Liu, HX
;
Gramatica, P
;
Li, JZ (reprint author), Lanzhou Univ, Sch Pharm, 199 West Donggang Rd, Lanzhou 730000, Peoples R China.
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  |  
浏览/下载:3/0
  |  
提交时间:2017/01/11
androgen receptor antagonist
comparative molecular field analysis
ligand efficiency
multiple linear regression
surface efficiency index
Lathyrol Diterpenes as Modulators of P-Glycoprotein Dependent Multidrug Resistance: Structure-Activity Relationship Studies on Euphorbia Factor L-3 Derivatives
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 9, 页码: 3720-3738
作者:
Jiao, Wei
;
Wan, Zhongmin
;
Chen, Shuang
;
Lu, Runhua
;
Chen, Xiaozhen
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  |  
浏览/下载:45/0
  |  
提交时间:2016/12/22
MOUSE LYMPHOMA-CELLS
JATROPHANE DITERPENES
BREAST-CANCER
MACROCYCLIC DITERPENES
PROTEIN STRUCTURES
DRUG-BINDING
DISCOVERY
TRANSPORTERS
GENERATION
DATABASE
A Combined Quantitative Structure-Activity Relationship Research of Quinolinone Derivatives as Androgen Receptor Antagonists
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2015, 卷号: 18, 期号: 9, 页码: 834-845
作者:
Wang, YW
;
Bai, F
;
Cao, H
;
Li, JZ
;
Liu, HX
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/01/11
Androgen receptor (AR)
comparative molecular field analysis (CoMFA)
prostate cancer (PCa)
comparative molecular similarity indices analysis (CoMSIA)
multiple linear regression (MLR)
Cardiac glycosides from the bark of Antiaris toxicaria
期刊论文
FITOTERAPIA, 2014, 卷号: 97, 页码: 71-77
作者:
Li, Xiao-San
;
Hu, Meng-Jie
;
Liu, Jie
;
Liu, Qian
;
Huang, Zhi-Xing
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  |  
浏览/下载:28/0
  |  
提交时间:2014/11/25
Antiaris toxicaria
Chemical constituents
Cardiac glycoside
Cytotoxicity
Expression of Nur77
First Total Syntheses and Antimicrobial Evaluation of Penicimonoterpene, a Marine-Derived Monoterpenoid, and Its Various Derivatives
期刊论文
MARINE DRUGS, 2014, 卷号: 12, 期号: 6, 页码: 3352-3370
作者:
Zhao, Jian-Chun
;
Li, Xiao-Ming
;
Gloer, James B.
;
Wang, Bin-Gui
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2015/06/11
(+/-)-penicimonoterpene
total synthesis
antimicrobial activity
structure-activity relationship
Synthesis and evaluation of immunostimulant plasmalogen lysophosphatidylethanolamine and analogues for natural killer T cells
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 11, 页码: 2966-2973
作者:
Ni, Guanghui
;
Li, Zhiyuan
;
Liang, Kangjiang
;
Wu, Ting
;
De Libero, Gennaro
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  |  
浏览/下载:24/0
  |  
提交时间:2014/06/23
NKT cells
Antigen
lysophospholipids
SAR
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